Literature DB >> 19590318

Impact of obesity in damage control laparotomy patients.

Juan C Duchesne1, Robert E Schmieg, Jon D Simmons, Tareq Islam, Clifton L McGinness, Norman E McSwain.   

Abstract

BACKGROUND: Obesity is an independent predictor of increased morbidity and mortality in critically injured trauma patients. We hypothesized that obese patients in need of damage control laparotomy (DCL) will encounter an increase incidence of postsurgical complications with a concomitant increase mortality when compared with a cohort of nonobese patients.
METHODS: All adult trauma patients who underwent DCL during a 4-year period at a Level I Trauma Center were retrospectively reviewed. Patients were categorized into nonobese (body mass index [BMI] < or = 29 kg/m), obese (BMI 30-39 kg/m), and severely obese (BMI > or = 40 kg/m) groups. Outcome measures included the occurrence of postoperative infectious complications, failure of primary abdominal wall fascial closure, acute respiratory distress syndrome, acute renal insufficiency, multiple system organ failure, days of ventilator support, hospital length of stay, and death.
RESULTS: During a 4-year period, 12,759 adult trauma patients were admitted to our Level I Trauma Center of which 1,812 (14.2%) underwent emergent laparotomy. Of these, 104 (5.7%) were treated with DCL: nonobese, n = 51 (49%); obese, n = 38 (37%); and severely obese, n = 15 (14%). In a multivariate adjusted model, multiple system organ failure was 1.82 times more likely in severely obese (95% CI: 1.14-2.90) and 1.74 times more likely in the obese patients (95% CI: 1.14-2.66) when compared with patients with normal BMI after DCL (p < 0.01). In the severely obese patients undergoing DCL, significantly elevated prevalence ratios (PR) for development of postoperative infectious complications, acute renal insufficiency, and failure of primary abdominal wall fascial closure were 1.75, 3.07, and 2.62, respectively. Days of ventilator support, length of stay, and mortality rates were significantly higher in severely obese patients (24 days, 27 days, and 60%) compared with obese (14 days, 14 days, and 21%) and nonobese (9.8 days, 14 days, and 28%) patients.
CONCLUSION: Severe obesity was significantly associated with adverse outcomes and increased resource utilization in trauma patients treated with DCL. Measures to improve outcomes in this vulnerable patient population must be directed at multiple levels of health care.

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Year:  2009        PMID: 19590318     DOI: 10.1097/TA.0b013e3181a92ce0

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  9 in total

1.  Open Abdomen in Obese Patients: Pay Attention! New Evidences from IROA, the International Register of Open Abdomen.

Authors:  Marco Ceresoli; Francesco Salvetti; Yoram Kluger; Marco Braga; Jacopo Viganò; Paola Fugazzola; Massimo Sartelli; Luca Ansaloni; Fausto Catena; Federico Coccolini
Journal:  World J Surg       Date:  2020-01       Impact factor: 3.352

2.  Damage control laparotomy utilization rates are highly variable among Level I trauma centers: Pragmatic, Randomized Optimal Platelet and Plasma Ratios findings.

Authors:  Justin Jeremiah Joseph Watson; Jamison Nielsen; Kyle Hart; Priya Srikanth; John D Yonge; Christopher R Connelly; Phillip M Kemp Bohan; Hillary Sosnovske; Barbara C Tilley; Gerald van Belle; Bryan A Cotton; Terence S OʼKeeffe; Eileen M Bulger; Karen J Brasel; John B Holcomb; Martin A Schreiber
Journal:  J Trauma Acute Care Surg       Date:  2017-03       Impact factor: 3.313

Review 3.  Trauma and BMI Mortality.

Authors:  Tejal S Brahmbhatt; Michael Hernon; Charles Jeffrey Siegert; Leneé Plauché; Lorrie S Young; Peter Burke
Journal:  Curr Obes Rep       Date:  2017-06

Review 4.  A growing problem: implications of obesity on the provision of trauma care.

Authors:  Ahmed Twaij; Mikael H Sodergren; Philip H Pucher; Nicola Batrick; Sanjay Purkayastha
Journal:  Obes Surg       Date:  2013-12       Impact factor: 4.129

5.  Effect of dietary conjugated linoleic acid supplementation on early inflammatory responses during cutaneous wound healing.

Authors:  Na-Young Park; Giuseppe Valacchi; Yunsook Lim
Journal:  Mediators Inflamm       Date:  2010-08-17       Impact factor: 4.711

6.  Protective Role of Obesity on Trauma Impact: A Retrospective Analysis of Patients with Surgical Blunt Bowel Mesenteric Injury Due to Road Traffic Accidents.

Authors:  Yueh-Wei Liu; Ching-Hua Hsieh; Ting-Min Hsieh; Po-Chun Chuang; Chun-Ting Liu; Bei-Yu Wu
Journal:  Risk Manag Healthc Policy       Date:  2022-08-18

7.  Operative management of acute abdomen after bariatric surgery in the emergency setting: the OBA guidelines.

Authors:  Belinda De Simone; Elie Chouillard; Almino C Ramos; Gianfranco Donatelli; Tadeja Pintar; Rahul Gupta; Federica Renzi; Kamal Mahawar; Brijesh Madhok; Stefano Maccatrozzo; Fikri M Abu-Zidan; Ernest E Moore; Dieter G Weber; Federico Coccolini; Salomone Di Saverio; Andrew Kirkpatrick; Vishal G Shelat; Francesco Amico; Emmanouil Pikoulis; Marco Ceresoli; Joseph M Galante; Imtiaz Wani; Nicola De' Angelis; Andreas Hecker; Gabriele Sganga; Edward Tan; Zsolt J Balogh; Miklosh Bala; Raul Coimbra; Dimitrios Damaskos; Luca Ansaloni; Massimo Sartelli; Nikolaos Parasas; Yoram Kluger; Elias Chahine; Vanni Agnoletti; Gustavo Fraga; Walter L Biffl; Fausto Catena
Journal:  World J Emerg Surg       Date:  2022-09-27       Impact factor: 8.165

8.  "Obesity Paradox" in Acute Respiratory Distress Syndrome: Asystematic Review and Meta-Analysis.

Authors:  Guo Zhi; Wang Xin; Wang Ying; Xing Guohong; Liu Shuying
Journal:  PLoS One       Date:  2016-09-29       Impact factor: 3.240

9.  Exploring the role of obesity and overweight in predicting postoperative outcome of abdominal surgery in a sub-Saharan African setting: a prospective cohort study.

Authors:  Benjamin Momo Kadia; Alain Chichom-Mefire; Gregory Edie Halle-Ekane
Journal:  BMC Res Notes       Date:  2018-10-19
  9 in total

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