Literature DB >> 19588751

[Augmentation of quality of wound healing of deep burn].

Xiao-yuan Huang1.   

Abstract

This article summarizes methods of repair of massive and deep wounds, elucidates how to improve wound healing quality and avoid scar deformity after deep burn. A part of denatured dermis (non-necrotic) in deep partial-thickness burn, "mixed degree" burn, even in full-thickness burn wounds before forming eschar can be preserved and covered with autologous skin, thereby to avoid secondary damage to the structure of subcutaneous tissue and the junction of dermis-adipose, thus to result in good functions, appearance, and survival rate. After skin grafting, wound healing quality and appearance are improved, joint function and elasticity of skin are enhanced, the degree of scar contracture is relieved due to preservation of normal adipose tissue after escharectomy. The study of composite artificial skin will be actively developed in the future. Tissue-engineering skin and stem cells can be successfully used in patients with deep burns for scarless healing with restoration of physiological functions in a short period.

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Mesh:

Year:  2009        PMID: 19588751

Source DB:  PubMed          Journal:  Zhonghua Shao Shang Za Zhi        ISSN: 1009-2587


  2 in total

1.  Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury.

Authors:  Jie Zhou; Xipeng Zhang; Pengfei Liang; Licheng Ren; Jizhang Zeng; Minghua Zhang; Pihong Zhang; Xiaoyuan Huang
Journal:  Biol Open       Date:  2016-01-21       Impact factor: 2.422

2.  Autophagy promotes angiogenesis via AMPK/Akt/mTOR signaling during the recovery of heat-denatured endothelial cells.

Authors:  Pengfei Liang; Bimei Jiang; Yuanbin Li; Zhenguo Liu; Pihong Zhang; Minghua Zhang; Xiaoyuan Huang; Xianzhong Xiao
Journal:  Cell Death Dis       Date:  2018-11-19       Impact factor: 8.469

  2 in total

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