Literature DB >> 19585625

Molecular mechanism of inhibition of the human protein complex Hsp90-Cdc37, a kinome chaperone-cochaperone, by triterpene celastrol.

Sridhar Sreeramulu1, Santosh Lakshmi Gande, Michael Göbel, Harald Schwalbe.   

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Year:  2009        PMID： 19585625     DOI： 10.1002/anie.200900929

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  66 in total

1.  Alternative approaches to Hsp90 modulation for the treatment of cancer.

Authors:  Jessica A Hall; Leah K Forsberg; Brian S J Blagg
Journal:  Future Med Chem       Date:  2014-09       Impact factor: 3.808

2.  Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment.

Authors:  Hardik J Patel; Shanu Modi; Gabriela Chiosis; Tony Taldone
Journal:  Expert Opin Drug Discov       Date:  2011-05       Impact factor: 6.098

3.  Split Renilla luciferase protein fragment-assisted complementation (SRL-PFAC) to characterize Hsp90-Cdc37 complex and identify critical residues in protein/protein interactions.

Authors:  Yiqun Jiang; Denzil Bernard; Yanke Yu; Yehua Xie; Tao Zhang; Yanyan Li; Joseph P Burnett; Xueqi Fu; Shaomeng Wang; Duxin Sun
Journal:  J Biol Chem       Date:  2010-04-22       Impact factor: 5.157

4.  The C-terminal domain of human Cdc37 studied by solution NMR.

Authors:  Ziming Zhang; Dimitra Keramisanou; Amit Dudhat; Michael Paré; Ioannis Gelis
Journal:  J Biomol NMR       Date:  2015-09-24       Impact factor: 2.835

Review 5.  A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond.

Authors:  Tony Taldone; Tai Wang; Anna Rodina; Naga Vara Kishore Pillarsetty; Chander S Digwal; Sahil Sharma; Pengrong Yan; Suhasini Joshi; Piyusha P Pagare; Alexander Bolaender; Gail J Roboz; Monica L Guzman; Gabriela Chiosis
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-04-01       Impact factor: 10.005

Review 6.  Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects.

Authors:  Gaurav Garg; Anuj Khandelwal; Brian S J Blagg
Journal:  Adv Cancer Res       Date:  2016-02-10       Impact factor: 6.242

7.  Molecular Mechanism of Protein Kinase Recognition and Sorting by the Hsp90 Kinome-Specific Cochaperone Cdc37.

Authors:  Dimitra Keramisanou; Adam Aboalroub; Ziming Zhang; Wenjun Liu; Devon Marshall; Andrea Diviney; Randy W Larsen; Ralf Landgraf; Ioannis Gelis
Journal:  Mol Cell       Date:  2016-04-21       Impact factor: 17.970

8.  Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis.

Authors:  Sean D Allen; Yu-Gang Liu; Taehyeung Kim; Sharan Bobbala; Sijia Yi; Xiaohan Zhang; Jaehyuk Choi; Evan A Scott
Journal:  Biomater Sci       Date:  2019-01-29       Impact factor: 6.843

9.  HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way.

Authors:  Bin Peng; Limin Xu; Fanfan Cao; Tingxuan Wei; Chunxin Yang; Georges Uzan; Denghai Zhang
Journal:  Mol Cancer       Date:  2010-04-16       Impact factor: 27.401

10.  Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.

Authors:  Daniel Paris; Nowell J Ganey; Vincent Laporte; Nikunj S Patel; David Beaulieu-Abdelahad; Corbin Bachmeier; Amelia March; Ghania Ait-Ghezala; Michael J Mullan
Journal:  J Neuroinflammation       Date:  2010-03-08       Impact factor: 8.322
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