Literature DB >> 19585051

Regioselective formation of interlocked dicarba bridges in naturally occurring cyclic peptide toxins using olefin metathesis.

Andrea J Robinson1, Bianca J van Lierop, Rebecca D Garland, Euneace Teoh, Jomana Elaridi, Jayamini P Illesinghe, W Roy Jackson.   

Abstract

Bis-dicarba analogues of native dicystine-containing alpha-conotoxin Rg1A, an analgesic peptide isolated from cone snail venom, were constructed on resin using a regioselective metathesis-hydrogenation strategy.

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Year:  2009        PMID： 19585051     DOI： 10.1039/b909056h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Peptide bicycles that inhibit the Grb2 SH2 domain.

Authors:  Justin S Quartararo; Pianpian Wu; Joshua A Kritzer
Journal:  Chembiochem       Date:  2012-06-11       Impact factor: 3.164

2.  Distinct disulfide isomers of μ-conotoxins KIIIA and KIIIB block voltage-gated sodium channels.

Authors:  Keith K Khoo; Kallol Gupta; Brad R Green; Min-Min Zhang; Maren Watkins; Baldomero M Olivera; Padmanabhan Balaram; Doju Yoshikami; Grzegorz Bulaj; Raymond S Norton
Journal:  Biochemistry       Date:  2012-11-28       Impact factor: 3.162

3.  Synthesis, conformational analysis and biological properties of a dicarba derivative of the antimicrobial peptide, brevinin-1BYa.

Authors:  Mohammed Akhter Hossain; Laure Guilhaudis; Agnes Sonnevend; Samir Attoub; Bianca J van Lierop; Andrea J Robinson; John D Wade; J Michael Conlon
Journal:  Eur Biophys J       Date:  2011-02-11       Impact factor: 1.733

4.  Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.

Authors:  Wen-Jian Qian; Jung-Eun Park; Robert Grant; Christopher C Lai; James A Kelley; Michael B Yaffe; Kyung S Lee; Terrence R Burke
Journal:  Biopolymers       Date:  2015-11       Impact factor: 2.505

Review 5.  Strategies for the development of conotoxins as new therapeutic leads.

Authors:  Ryan M Brady; Jonathan B Baell; Raymond S Norton
Journal:  Mar Drugs       Date:  2013-06-28       Impact factor: 5.118

6.  Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides.

Authors:  Philipp M Cromm; Sebastian Schaubach; Jochen Spiegel; Alois Fürstner; Tom N Grossmann; Herbert Waldmann
Journal:  Nat Commun       Date:  2016-04-14       Impact factor: 14.919
  6 in total

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