Literature DB >> 19583947

A crystallized view of AMPK activation.

Lawrence H Young1.   

Abstract

AMP-activated protein kinase (AMPK) is a key metabolic regulator. Recent work (Chen et al., 2009) elucidates the structural interaction between the autoinhibitory sequence and the kinase domain of the AMPK catalytic subunit. Enhanced understanding of the molecular mechanics of AMPK activation might lead to novel therapeutic approaches.

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Year:  2009        PMID： 19583947     DOI： 10.1016/j.cmet.2009.06.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  10 in total

1.  Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in Type 1 diabetic murine cardiomyocytes.

Authors:  Chao Tong; Alex Morrison; Xiaoyan Yan; Peng Zhao; Eddie D Yeung; Jingying Wang; Jianxin Xie; Ji Li
Journal:  J Diabetes       Date:  2010-12       Impact factor: 4.006

2.  The effects of dietary β-guanidinopropionic acid on growth and muscle fiber development in juvenile red porgy, Pagrus pagrus.

Authors:  Dalon P White; Bradley L Baumgarner; Wade O Watanabe; Md Shah Alam; Stephen T Kinsey
Journal:  Comp Biochem Physiol B Biochem Mol Biol       Date:  2017-11-22       Impact factor: 2.231

3.  The protective effect of trimetazidine on myocardial ischemia/reperfusion injury through activating AMPK and ERK signaling pathway.

Authors:  Zhenling Liu; Ji-Mei Chen; Huanlei Huang; Michelle Kuznicki; Shaoyi Zheng; Wanqing Sun; Nanhu Quan; Lin Wang; Hui Yang; Hui-Ming Guo; Ji Li; Jian Zhuang; Ping Zhu
Journal:  Metabolism       Date:  2015-10-19       Impact factor: 8.694

4.  AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice.

Authors:  Yu Li; Shanqin Xu; Maria M Mihaylova; Bin Zheng; Xiuyun Hou; Bingbing Jiang; Ogyi Park; Zhijun Luo; Etienne Lefai; John Y-J Shyy; Bin Gao; Michel Wierzbicki; Tony J Verbeuren; Reuben J Shaw; Richard A Cohen; Mengwei Zang
Journal:  Cell Metab       Date:  2011-04-06       Impact factor: 27.287

5.  The dynamical mechanism of auto-inhibition of AMP-activated protein kinase.

Authors:  Cheng Peng; Teresa Head-Gordon
Journal:  PLoS Comput Biol       Date:  2011-07-21       Impact factor: 4.475

6.  AMPK Activators as a Drug for Diabetes, Cancer and Cardiovascular Disease.

Authors:  Mark Goodman; Zhenling Liu; Ping Zhu; Ji Li
Journal:  Pharm Regul Aff       Date:  2014-04-03

7.  Citral Induced Apoptosis through Modulation of Key Genes Involved in Fatty Acid Biosynthesis in Human Prostate Cancer Cells: In Silico and In Vitro Study.

Authors:  Sri Renukadevi Balusamy; Haribalan Perumalsamy; Karpagam Veerappan; Md Amdadul Huq; S Rajeshkumar; T Lakshmi; Yeon Ju Kim
Journal:  Biomed Res Int       Date:  2020-03-18       Impact factor: 3.411

8.  Update on berberine in nonalcoholic Fatty liver disease.

Authors:  Yang Liu; Li Zhang; Haiyan Song; Guang Ji
Journal:  Evid Based Complement Alternat Med       Date:  2013-06-17       Impact factor: 2.629

9.  Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation.

Authors:  Chunyi Wang; Yan Li; Mengjiao Hao; Weimin Li
Journal:  Front Pharmacol       Date:  2018-04-16       Impact factor: 5.810

10.  Overexpression of miR-1298 attenuates myocardial ischemia-reperfusion injury by targeting PP2A.

Authors:  Chun Ouyang; Lei Huang; Xiaoqiang Ye; Mingming Ren; Zhen Han
Journal:  J Thromb Thrombolysis       Date:  2021-08-05       Impact factor: 2.300
  10 in total

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