Literature DB >> 19583783

Prevalence, incidence, and clinical characteristics of epilepsy--a community-based door-to-door study in northern Tanzania.

Andrea S Winkler1, Kerstin Kerschbaumsteiner, Brigitte Stelzhammer, Michael Meindl, John Kaaya, Erich Schmutzhard.   

Abstract

PURPOSE: The main aim of this door-to-door-study was to determine the prevalence, incidence, and clinical characteristics of epilepsy in northern Tanzania.
METHODS: A total of 7,399 people were screened with a standardized questionnaire using "multistage random sampling."
RESULTS: The prevalence rate of epilepsy was 11.2/1,000 [95% confidence interval (CI) 8.9-13.9/1,000] and the age-adjusted prevalence rate was 13.2/1,000. The prevalence of active epilepsy was 8.7/1,000 (95% CI 6.7-11/1,000). There was a preponderance of women. The average retrospective incidence including the last 5 years was 81.1/100,000 (95% CI 65-101/100,000). Fifty-four percent (45 of 83) of the people with epilepsy had generalized seizures without any identifiable cause; 71% (59 of 83) of the epilepsy patients had not visited health institutions prior to the study and 76% (63 of 83) had never received treatment. DISCUSSION: Our study shows that the prevalence and incidence of epilepsy in northern Tanzania are higher compared to developed countries and that the majority of people with epilepsy do not access treatment.

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Year:  2009        PMID: 19583783     DOI: 10.1111/j.1528-1167.2009.02184.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  25 in total

Review 1.  Epidemiology, causes, and treatment of epilepsy in sub-Saharan Africa.

Authors:  Awa Ba-Diop; Benoît Marin; Michel Druet-Cabanac; Edgard B Ngoungou; Charles R Newton; Pierre-Marie Preux
Journal:  Lancet Neurol       Date:  2014-10       Impact factor: 44.182

2.  Cysticercosis and epilepsy in rural Tanzania: a community-based case-control and imaging study.

Authors:  Ewan Hunter; Kathryn Burton; Ahmed Iqbal; Daniel Birchall; Margaret Jackson; Jane Rogathe; Ahmed Jusabani; William Gray; Eric Aris; Gathoni Kamuyu; Patricia P Wilkins; Charles R Newton; Richard Walker
Journal:  Trop Med Int Health       Date:  2015-05-26       Impact factor: 2.622

Review 3.  Sex differences in the neurobiology of epilepsy: a preclinical perspective.

Authors:  Helen E Scharfman; Neil J MacLusky
Journal:  Neurobiol Dis       Date:  2014-07-21       Impact factor: 5.996

Review 4.  Neurocysticercosis in sub-Saharan Africa: a review of prevalence, clinical characteristics, diagnosis, and management.

Authors:  Andrea Sylvia Winkler
Journal:  Pathog Glob Health       Date:  2012-09       Impact factor: 2.894

Review 5.  Epilepsy and neurocysticercosis in sub-Saharan Africa.

Authors:  Andrea Sylvia Winkler; Arve Lee Willingham; Chummy Sikalizyo Sikasunge; Erich Schmutzhard
Journal:  Wien Klin Wochenschr       Date:  2009-10       Impact factor: 1.704

6.  Validity of a screening instrument for neurologic disability in resource-poor African communities.

Authors:  James H Bower; Emanuel Mwendo; Richard Walker; Venance Maro; Fikre Enquosellasie; Seid Ali
Journal:  J Neurol Sci       Date:  2012-07-11       Impact factor: 3.181

7.  Epilepsy in Tanzanian children: association with perinatal events and other risk factors.

Authors:  Kathryn J Burton; Jane Rogathe; Roger Whittaker; Kshitij Mankad; Ewan Hunter; Matthew J Burton; Jim Todd; Brian G R Neville; Richard Walker; Charles R J C Newton
Journal:  Epilepsia       Date:  2012-02-06       Impact factor: 5.864

Review 8.  Toxocariasis and epilepsy: systematic review and meta-analysis.

Authors:  Graziella Quattrocchi; Alessandra Nicoletti; Benoit Marin; Elisa Bruno; Michel Druet-Cabanac; Pierre-Marie Preux
Journal:  PLoS Negl Trop Dis       Date:  2012-08-14

9.  Clinical and neurophysiologic features of active convulsive epilepsy in rural Kenya: a population-based study.

Authors:  Gilbert Munyoki; Tansy Edwards; Steve White; Thomas Kwasa; Eddie Chengo; Gilbert Kokwaro; Victor Mung'ala Odera; Josemir W Sander; Brian G Neville; Charles R Newton
Journal:  Epilepsia       Date:  2010-12       Impact factor: 5.864

10.  Lifetime prevalence of epilepsy in urban Tanzania - A door-to-door random cluster survey.

Authors:  Dominik Stelzle; Veronika Schmidt; Bernard J Ngowi; William Matuja; Erich Schmutzhard; Andrea S Winkler
Journal:  eNeurologicalSci       Date:  2021-06-15
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