Literature DB >> 19582291

Recent highlights in the synthesis of highly functionalized pyrimidines.

Marco Radi1, Silvia Schenone, Maurizio Botta.   

Abstract

The pyrimidine scaffold represents an important pharmacophore endowed with a wide range of pharmacological activities according to the specific decoration of the heterocycle. This perspective article will briefly outline the most interesting approaches recently reported for the synthesis of highly functionalized pyrimidine derivatives.

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Year:  2009        PMID: 19582291     DOI: 10.1039/b906445a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  3 in total

1.  Mild Reductive Functionalization of Amides into N-Sulfonylformamidines.

Authors:  Paz Trillo; Tove Slagbrand; Fredrik Tinnis; Hans Adolfsson
Journal:  ChemistryOpen       Date:  2017-07-03       Impact factor: 2.911

2.  Triazine bis(pyridinium) hydrogen sulfate ionic liquid immobillized on functionalized halloysite nanotubes as an efficient catalyst for one-pot synthesis of naphthopyranopyrimidines.

Authors:  Marzieh Samadani; Beheshteh Asadi; Iraj Mohammadpoor-Baltork; Valiollah Mirkhani; Shahram Tangestaninejad; Majid Moghadam
Journal:  RSC Adv       Date:  2021-03-23       Impact factor: 3.361

3.  Naturally Inspired Pyrimidines Analogues for Alzheimer's Disease.

Authors:  Shivani Singh; Meenakshi Dhanawat; Sumeet Gupta; Deepak Kumar; Saloni Kakkar; Anroop Nair; Inderjeet Verma; Prerna Sharma
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363

  3 in total

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