Literature DB >> 19581140

Reconstruction of the hypopharynx after surgical treatment of squamous cell carcinoma.

Pen-Yuan Chu1, Shyue-Yih Chang.   

Abstract

Squamous cell carcinoma of the hypopharynx (HPSCC) tends to present with an advanced stage. Surgery with postoperative radiation or chemoradiation therapy has been the standard treatment for HPSCC. Radical surgery may result in a large surgical defect of the hypopharyngeal and cervical esophageal regions. Reconstruction of the surgical defect is also important after ablation procedures. Many reconstructive methods have been developed. However, each method has its own advantages and disadvantages. The ideal method for hypopharyngeal reconstruction should have the following attributes if possible: single-stage procedure, high success rate of tissue transfer, low donor-site morbidity, low fistula and stenosis rates, restoration of the ability to speak and swallow, able to achieve successful reconstruction in a heavily radiated area and tolerance of postoperative radiotherapy. In this review article, we discuss the indications and drawbacks of several reconstructive methods that have been frequently used in our clinical practice. Finally, we will introduce the technique of laryngotracheal flap reconstruction, which was developed in our institution and has proved to be a simple and reliable method for hypopharyngeal reconstruction.

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Year:  2009        PMID: 19581140     DOI: 10.1016/S1726-4901(09)70386-7

Source DB:  PubMed          Journal:  J Chin Med Assoc        ISSN: 1726-4901            Impact factor:   2.743


  12 in total

1.  Interaction between TNFR1 and TNFR2 dominates the clinicopathologic features of human hypopharyneal carcinoma.

Authors:  Xiuru Ma; Xiaoming Li; Xiuying Lu; Lifeng Jia; Hui Li; Qi Song
Journal:  Tumour Biol       Date:  2015-06-27

2.  Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.

Authors:  Arron Sikka; Manjinder Kaur; Chapla Agarwal; Gagan Deep; Rajesh Agarwal
Journal:  Cell Cycle       Date:  2012-04-01       Impact factor: 4.534

3.  Delayed reconstruction of the upper digestive tract in a patient following total pharyngolaryngectomy with resection of the cervical oesophagus.

Authors:  Mateusz Szewczyk; Jakub Pazdrowski; Paweł Golusiński; Wojciech Golusiński
Journal:  Rep Pract Oncol Radiother       Date:  2014-12-23

4.  Radial forearm free flap as the last resort for oesophageal reconstruction.

Authors:  E A Griffiths; N Iqbal; T Martin; A Ranasinghe; S Parmar
Journal:  Ann R Coll Surg Engl       Date:  2018-08-16       Impact factor: 1.891

5.  Evaluation of Bilayer Silk Fibroin Grafts for Tubular Esophagoplasty in a Porcine Defect Model.

Authors:  Gokhan Gundogdu; Duncan Morhardt; Vivian Cristofaro; Khalid Algarrahi; Xuehui Yang; Kyle Costa; Cinthia Galvez Alegria; Maryrose P Sullivan; Joshua R Mauney
Journal:  Tissue Eng Part A       Date:  2020-06-26       Impact factor: 3.845

6.  Advanced carcinoma of the hypopharynx: functional results after circumferential pharyngolaryngectomy with flap reconstruction.

Authors:  F Mura; G Bertino; A Occhini; N Mevio; D Scelsi; M Benazzo
Journal:  Acta Otorhinolaryngol Ital       Date:  2012-06       Impact factor: 2.124

7.  Use of Supraclavicular Flap by End to Side Technique in Pharyngeal SCC: A Case Report and Review of Literature.

Authors:  Aslan Ahmadi; Ayda Sanaei; Delaram Jan; Maryam Zolfaghary
Journal:  Case Rep Otolaryngol       Date:  2021-07-14

Review 8.  Surgical treatment of hypopharyngeal cancer: a review of the literature and proposal for a decisional flow-chart.

Authors:  F Mura; G Bertino; A Occhini; M Benazzo
Journal:  Acta Otorhinolaryngol Ital       Date:  2013-10       Impact factor: 2.124

9.  Downregulation of RNA binding motif protein 17 expression inhibits proliferation of hypopharyngeal carcinoma FaDu cells.

Authors:  Yuefeng Han; Mingjie Zhang; Deshang Chen; Hui Li; Xiaomin Wang; Shiyin Ma
Journal:  Oncol Lett       Date:  2018-02-09       Impact factor: 2.967

10.  Involvement of Differentially Expressed microRNAs in the PEGylated Liposome Encapsulated 188Rhenium-Mediated Suppression of Orthotopic Hypopharyngeal Tumor.

Authors:  Bing-Ze Lin; Shen-Ying Wan; Min-Ying Lin; Chih-Hsien Chang; Ting-Wen Chen; Muh-Hwa Yang; Yi-Jang Lee
Journal:  Molecules       Date:  2020-08-08       Impact factor: 4.411

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