| Literature DB >> 19581055 |
Abstract
Wilson's disease is a rare genetic illness of copper metabolism, which leads to copper-overload in mitochondria and organ damage, especially to the liver. Oxidative stress is central to the pathogenesis and a case is briefly made for rigorous trials of vitamin E as an antioxidant adjunct based on earlier corollary studies of its levels in the blood and liver of Wilson's disease patients and its effects in animal models of the illness.Entities:
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Year: 2009 PMID： 19581055 DOI： 10.1016/j.mehy.2009.05.025
Source DB: PubMed Journal: Med Hypotheses ISSN： 0306-9877 Impact factor: 1.538