| Literature DB >> 1958099 |
M Brzeski1, L Smart, D Baird, R Jackson, R Sturrock.
Abstract
A patient with Felty's syndrome who developed bilateral knee septic arthritis and septicaemia due to Streptococcus pneumoniae is described. She had had a previous splenectomy for symptomatic thrombocytopenia, having received pneumococcal vaccine before the operation. Measurement of antibody to the 23 vaccine serotypes showed protective concentrations before infection to just two. The infecting serotype was not represented in the vaccine, but a vigorous antibody response to this serotype occurred. The patient also developed glomerulonephritis due to immune complex deposition.Entities:
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Year: 1991 PMID: 1958099 PMCID: PMC1004541 DOI: 10.1136/ard.50.10.724
Source DB: PubMed Journal: Ann Rheum Dis ISSN: 0003-4967 Impact factor: 19.103