INTRODUCTION AND OBJECTIVE: Some candidates for brachytherapy present with a previous history of prostate transurethral resection (TURP). Nonetheless, TURP generates a cavity that may lead to technical difficulties in performing brachytherapy. Such condition make a history of previous TURP a relative contra-indication for brachytherapy. The aim of this study is to evaluate the role of brachytherapy in urinary continence, in a group of patients with previous history of TURP. MATERIALS AND METHODS: In our study, we analysed a group of 16 patients submitted to TURP pre-brachytherapy. The mean quality of life score from ICSmaleSF questionnaire ranged from 0 to 1 before and after brachytheraphy (average: 0,18 -- before; average: 0,20 -- after). There was no estatistically significant difference between the former values (p<0,001). After brachytherapy patients were evaluated for lower urinary tract symptoms. The time interval between TURP and brachytherapy ranged from 30 to 90 days (average: 60 days). Post-brachytherapy follow-up varied between 3 and 60 months (average: 30 months). RESULTS: None of the 16 patients evaluated presented lower urinary tract symptoms nor urinary incontinence. Medical complications observed in patients were: dysuria, erectile dysfunction, scrotal ecchymosis and urinary retention. The cases of dysuria, scrotal ecchymosis and urinary retention observed were of short-duration, the last one with spontaneous resolution after 7 days of vesical catheterism. The patient presenting erectile dysfunction had a good response to oral type 5 fosfodiesterase inhibitor three times a week, after a six month period. CONCLUSION: In accordance with other studies, we believe that with some strategy TURP should not be considered a relative contra-indication for brachytherapy.
INTRODUCTION AND OBJECTIVE: Some candidates for brachytherapy present with a previous history of prostate transurethral resection (TURP). Nonetheless, TURP generates a cavity that may lead to technical difficulties in performing brachytherapy. Such condition make a history of previous TURP a relative contra-indication for brachytherapy. The aim of this study is to evaluate the role of brachytherapy in urinary continence, in a group of patients with previous history of TURP. MATERIALS AND METHODS: In our study, we analysed a group of 16 patients submitted to TURP pre-brachytherapy. The mean quality of life score from ICSmaleSF questionnaire ranged from 0 to 1 before and after brachytheraphy (average: 0,18 -- before; average: 0,20 -- after). There was no estatistically significant difference between the former values (p<0,001). After brachytherapy patients were evaluated for lower urinary tract symptoms. The time interval between TURP and brachytherapy ranged from 30 to 90 days (average: 60 days). Post-brachytherapy follow-up varied between 3 and 60 months (average: 30 months). RESULTS: None of the 16 patients evaluated presented lower urinary tract symptoms nor urinary incontinence. Medical complications observed in patients were: dysuria, erectile dysfunction, scrotal ecchymosis and urinary retention. The cases of dysuria, scrotal ecchymosis and urinary retention observed were of short-duration, the last one with spontaneous resolution after 7 days of vesical catheterism. The patient presenting erectile dysfunction had a good response to oral type 5 fosfodiesterase inhibitor three times a week, after a six month period. CONCLUSION: In accordance with other studies, we believe that with some strategy TURP should not be considered a relative contra-indication for brachytherapy.
Authors: Pedro J Prada; Javier Anchuelo; Ana Garcia Blanco; Gema Paya; Juan Cardenal; Enrique Acuna; Maria Ferri; Andres Vazquez; Maite Pacheco; Jesica Sanchez Journal: Int Braz J Urol Date: 2016 Jan-Feb Impact factor: 1.541