| Literature DB >> 19579699 |
Abbas Doosti1, Samad Amini-Bavil-Olyaee, Elaheh Tajbakhsh, Ahmad Adeli, Fereidoun Mahboudi.
Abstract
To determine the prevalence of viral hepatitis infection and hepatitis B virus (HBV) molecular characterization, 11,200 blood donors from citizens of Shahrekord (a city located in west of Iran) were investigated. Results showed HBsAg-positive in 1.78% of persons (n=200), anti-HDV-positive in 3% of HBsAg-positive cases (n=6) and anti-HCV-positive in 0.67% of donors (n=76). HBV phylogenetic analysis disclosed HBV genotype D, sub-genotype D1, and subtype ayw2. Amino acid mapping of the HBV pol region revealed various HBV drug-resistance mutations though donors had no antiviral therapy. In conclusion, this study demonstrated notable viral hepatitis seroprevalence rate in blood donors in west of Iran.Entities:
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Year: 2009 PMID: 19579699
Source DB: PubMed Journal: New Microbiol ISSN: 1121-7138 Impact factor: 2.479