Literature DB >> 19577613

On the evolution of scale-free topologies with a gene regulatory network model.

Miguel Nicolau1, Marc Schoenauer.   

Abstract

A novel approach to generating scale-free network topologies is introduced, based on an existing artificial gene regulatory network model. From this model, different interaction networks can be extracted, based on an activation threshold. By using an evolutionary computation approach, the model is allowed to evolve, in order to reach specific network statistical measures. The results obtained show that, when the model uses a duplication and divergence initialisation, such as seen in nature, the resulting regulation networks not only are closer in topology to scale-free networks, but also require only a few evolutionary cycles to achieve a satisfactory error value.

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Year:  2009        PMID: 19577613     DOI: 10.1016/j.biosystems.2009.06.006

Source DB:  PubMed          Journal:  Biosystems        ISSN: 0303-2647            Impact factor:   1.973


  3 in total

1.  Pleiotropy constrains the evolution of protein but not regulatory sequences in a transcription regulatory network influencing complex social behaviors.

Authors:  Daria Molodtsova; Brock A Harpur; Clement F Kent; Kajendra Seevananthan; Amro Zayed
Journal:  Front Genet       Date:  2014-12-23       Impact factor: 4.599

Review 2.  Graphics Processing Unit-Enhanced Genetic Algorithms for Solving the Temporal Dynamics of Gene Regulatory Networks.

Authors:  Raúl García-Calvo; J L Guisado; Fernando Diaz-Del-Rio; Antonio Córdoba; Francisco Jiménez-Morales
Journal:  Evol Bioinform Online       Date:  2018-04-10       Impact factor: 1.625

3.  Three topological features of regulatory networks control life-essential and specialized subsystems.

Authors:  Ivan Rodrigo Wolf; Rafael Plana Simões; Guilherme Targino Valente
Journal:  Sci Rep       Date:  2021-12-20       Impact factor: 4.379

  3 in total

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