Literature DB >> 1957662

[Chemical studies of Salvia miltiorrhiza f. alba].

Z T Li1, B J Yang, G E Ma.   

Abstract

Fourteen constituents were isolated from the roots of Salvia miltiorrhiza f. alba. Two of them were new compounds and were named 1,2,15,16-tetrahydrotanshiquinone (I) and tanshinaldehyde (II). The others were identified as Ro-090680 (III), dihydroisotanshone I (IV), danshexinkun B (V), miltirone (VI), nortanshinone (VII), hydroxytanshinone II-A (VIII), tanshinone I (IX), dihydrotanshinone I (X), tanshinone II-A (XI), cryptotanshinone (XII), methylenetanshiquinone (XIII), methyltanshinonate (XIV), I and III showed inhibitory activity against P388 Leukemia cell in vitro. III was reported to be a potent inhibitor of rabbit platelet aggregation induced by collagen.

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Year:  1991        PMID: 1957662

Source DB:  PubMed          Journal:  Yao Xue Xue Bao        ISSN: 0513-4870


  6 in total

1.  Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility.

Authors:  Jonah Cheung; Ebony N Gary; Kazuro Shiomi; Terrone L Rosenberry
Journal:  ACS Med Chem Lett       Date:  2013-09-23       Impact factor: 4.345

Review 2.  Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination.

Authors:  Jonah Cheung; Veena Beri; Kazuro Shiomi; Terrone L Rosenberry
Journal:  J Mol Neurosci       Date:  2014-02-27       Impact factor: 3.444

3.  Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells.

Authors:  Shu-Lan Yuan; Yu-Quan Wei; Xiu-Jie Wang; Fei Xiao; Sheng-Fu Li; Jie Zhang
Journal:  World J Gastroenterol       Date:  2004-07-15       Impact factor: 5.742

4.  Tanshinone IIA inhibits human breast cancer MDA-MB-231 cells by decreasing LC3-II, Erb-B2 and NF-κBp65.

Authors:  Chin-Cheng Su; Su-Yu Chien; Shou-Jen Kuo; Yao-Li Chen; Chun-Yuan Cheng; Dar-Ren Chen
Journal:  Mol Med Rep       Date:  2012-01-13       Impact factor: 2.952

5.  Molecular Mechanism of Salvia miltiorrhiza Bunge in Treating Cerebral Infarction.

Authors:  Xietao Ye; Jiali Liu; Xinyao Yuan; Songhong Yang; Yi Huang; Yan Chen
Journal:  Evid Based Complement Alternat Med       Date:  2022-03-29       Impact factor: 2.629

6.  Inhibition of Hypoxia Inducible Factor Alpha and Astrocyte-Elevated Gene-1 Mediates Cryptotanshinone Exerted Antitumor Activity in Hypoxic PC-3 Cells.

Authors:  Hyo-Jeong Lee; Deok-Beom Jung; Eun Jung Sohn; Hanna Hyun Kim; Moon Nyeo Park; Jae-Hwan Lew; Seok Geun Lee; Bonglee Kim; Sung-Hoon Kim
Journal:  Evid Based Complement Alternat Med       Date:  2012-11-29       Impact factor: 2.629

  6 in total

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