Literature DB >> 19575344

[Onyx (ethylene-vinyl-alcohol-copolymer)--a novel approach to the endovascular treatment of acute bleeding].

R Müller-Wille1, T Herold, E M Jung, J Rennert, P Heiss, M Lenhart, C Paetzel, S Feuerbach, N Zorger.   

Abstract

PURPOSE: The purpose of our retrospective study was to determine the feasibility and efficacy of the endovascular embolization of peripheral acute arterial hemorrhage using Onyx.
MATERIALS AND METHODS: Between October 2003 and February 2007, 14 patients with acute arterial bleeding underwent percutaneous arterial embolization using Onyx. Bleeding was caused by iatrogenic vessel injury (6 patients), malignancy/inflammation (5 patients) and trauma (3 patients). Hematomas were located in the pelvis (5 patients), followed by liver (3 patients), retroperitoneal space (2 patients), thorax (2 patients), pancreas (1 patient), and thigh (1 patient). The number of embolized arteries, the volume and viscosity of embolic agent (Onyx), the number of additionally used coils, the embolization time, and the technical and clinical outcome were documented. Procedure-related complications, recurrent bleeding during hospital stay and outcome were recorded.
RESULTS: In 14 patients selective endovascular embolization of 15 arteries was performed. The average volume of injected Onyx was 1.3 +/- 0.8 ml. In 6 cases (42.9%) Onyx was used in conjunction with coils. The average time between the correct placement of microcatheter and complete embolization was 24.9 +/- 12.6 minutes. In 13 of 14 patients (92.8%), embolization was technically successful. In one case, procedure-related complications occurred and embolization was performed in a second session a day later. After technically successful embolization, no recurrent bleeding occurred during hospitalization. Out of 14 patients, six (42.9%) died 1 - 38 days after technically successful embolization due to multiple organ failure (2 patients), hypoxic brain injury (2 patients), septic shock (1 patient) or malignancy-associated death (1 patient).
CONCLUSION: We conclude that transcatheter embolization with the new liquid embolic agent Onyx is technically feasible and effective in patients with acute arterial hemorrhage.

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Year:  2009        PMID: 19575344     DOI: 10.1055/s-0028-1109446

Source DB:  PubMed          Journal:  Rofo        ISSN: 1438-9010


  5 in total

1.  The use of Onyx for embolization of peripheral vascular malformations in pediatric patients.

Authors:  Murat Cantasdemir; Fatih Gulsen; Serdar Solak; Gokce Yalcin Gulsen; Fatih Kantarci; Furuzan Numan
Journal:  Pediatr Surg Int       Date:  2012-01-22       Impact factor: 1.827

2.  [Liquid embolic agents--Onyx as problem solver].

Authors:  W A Wohlgemuth; W Uller; R Müller-Wille
Journal:  Radiologe       Date:  2013-03       Impact factor: 0.635

Review 3.  [Biliodigestive anastomosis: indications, complications and interdisciplinary management].

Authors:  H Goessmann; S A Lang; S Fichtner-Feigl; M N Scherer; H J Schlitt; C Stroszczynski; A G Schreyer; A A Schnitzbauer
Journal:  Chirurg       Date:  2012-12       Impact factor: 0.955

4.  Liquid Embolization with Onyx in a Technically Challenging Case of Acute Upper GI Bleeding.

Authors:  Arindam Bharadwaz; Gayatri Madhab
Journal:  Indian J Surg       Date:  2013-03-14       Impact factor: 0.656

5.  [Hepatic trauma. Interventional and conservative therapy].

Authors:  M Loss; N Zorger; G I Kirchner; H J Schlitt
Journal:  Chirurg       Date:  2009-10       Impact factor: 0.955

  5 in total

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