| Literature DB >> 19575167 |
P Hanusch1, J Heyn, H Well, E Weninger, U Hasbargen, M Rehm.
Abstract
Friedreich's ataxia (FA) is a hereditary disease, which leads to degenerative changes in the spinal cord and cerebellum (incidence 1:50,000). These changes are caused by a defect in the gene that encodes a mitochondrial gene called frataxin and causes muscle weakness, scoliosis, cardiomyopathy and impaired glucose tolerance. Therefore, these patients require special care during anaesthesia. We report the case of a 25-year-old primigravida with a history of FA and dorsal stabilisation of the vertebral column, who was admitted to our hospital for elective caesarean section. Due to increased sensitivity to muscle relaxants, peridural anaesthesia with 8 ml 0.75% ropivacaine and 10 microg sufentanil was used in this case. The perioperative neurological consultation revealed no undue exacerbation of symptoms.Entities:
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Year: 2009 PMID: 19575167 DOI: 10.1007/s00101-009-1579-z
Source DB: PubMed Journal: Anaesthesist ISSN: 0003-2417 Impact factor: 1.041