Literature DB >> 1957348

Hexokinase and 'glucokinase' in liver metabolism.

A Cornish-Bowden1, M L Cárdenas.   

Abstract

Rat liver contains four hexokinase isoenzymes, one of which, despite often being called 'glucokinase', is no more specific for glucose than the others. However, it does differ from them in displaying a sigmoid kinetic response to glucose, requiring much higher glucose concentrations for activity, and being insensitive to physiological concentrations of glucose 6-phosphate.

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Year:  1991        PMID： 1957348     DOI： 10.1016/0968-0004(91)90115-c

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  3 in total

1.  The glucose sensor protein glucokinase is expressed in glucagon-producing alpha-cells.

Authors:  H Heimberg; A De Vos; K Moens; E Quartier; L Bouwens; D Pipeleers; E Van Schaftingen; O Madsen; F Schuit
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

Review 2.  Hexokinase domain-containing protein-1 in metabolic diseases and beyond.

Authors:  Joseph L Zapater; Kristen R Lednovich; Md Wasim Khan; Carolina M Pusec; Brian T Layden
Journal:  Trends Endocrinol Metab       Date:  2021-11-12       Impact factor: 12.015

3.  Intracellular pH governs the subcellular distribution of hexokinase in a glioma cell line.

Authors:  L Miccoli; S Oudard; F Sureau; F Poirson; B Dutrillaux; M F Poupon
Journal:  Biochem J       Date:  1996-02-01       Impact factor: 3.857
  3 in total

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