| Literature DB >> 19572746 |
Yiming Huang1, Vimal P Swarup, Sandra Whaley Bishnoi.
Abstract
Two Raman-active poly(ethylene glycol) (PEG) molecules, one linear (MW 5000) and the other branched (MW 2420), are synthesized to stabilize gold-silica nanoshells in cell culture media and track nanoparticles in mammalian cell cultures. The linear PEG provides greater nanoshell stability in saline solution compared to commercially available PEG-thiol or the branched PEG. Surface enhanced Raman scattering rapidly tracks the probes and provides semiquantitative information regarding particle localization within mouse macrophage (RAW 264.7) and human breast cancer (MCF 7) cell cultures.Entities:
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Year: 2009 PMID: 19572746 DOI: 10.1021/nl901234x
Source DB: PubMed Journal: Nano Lett ISSN: 1530-6984 Impact factor: 11.189