Literature DB >> 19572396

Comparison among different available surgical approaches in T1 glottic cancer.

Alexander D Karatzanis1, George Psychogios, Johannes Zenk, Frank Waldfahrer, Joachim Hornung, George A Velegrakis, Heinrich Iro.   

Abstract

OBJECTIVES/HYPOTHESIS: This study aims to assess the oncologic results of open and transoral surgical techniques in T1a and T1b category glottic carcinomas. STUDY
DESIGN: Retrospective clinical study.
METHODS: The files of 438 T1a and T1b glottic cancer cases managed with primary surgery were reviewed. Transoral laser surgery and open surgical procedures used to treat these cases, including cordectomy, vertical partial laryngectomy, and frontolateral partial laryngectomy, were compared for disease specific survival and local control rates. In addition, all techniques were compared for incidence of major complications and related tracheotomies.
RESULTS: No statistically significant differences were noted between laser surgery and open procedures with regard to disease specific survival and local control for both T1a and T1b cases. Laser surgery showed a significantly lower incidence of complications and tracheotomies.
CONCLUSIONS: Laser surgery appears to be a very effective management modality for T1 glottic cancer with comparable results to open procedures and a lower incidence of complications. A transcervical approach should be reserved only for selected cases where individual anatomic factors do not permit complete tumor exposure during diagnostic microlaryngoscopy.

Entities:  

Mesh:

Year:  2009        PMID: 19572396     DOI: 10.1002/lary.20537

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  17 in total

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4.  Multicentric evaluation of strategies for treatment of T1a glottic carcinomas.

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Journal:  Eur Arch Otorhinolaryngol       Date:  2014-08-09       Impact factor: 2.503

5.  Evaluation of lasersurgery and radiotherapy as treatment modalities in early stage laryngeal carcinoma: tumour outcome and quality of voice.

Authors:  A J Remmelts; F J P Hoebers; W M C Klop; A J M Balm; O Hamming-Vrieze; M W M van den Brekel
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-04-09       Impact factor: 2.503

6.  Introduction of a New Pathology Workup Protocol for Glottic Cancer Treated With Transoral Laser Microsurgery (TLM): Prospective Analysis of Oncological Outcomes and Matched Case-Control Study.

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7.  Functional organ preservation in laryngeal and hypopharyngeal cancer.

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Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2012-04-26

8.  The cadherin-catenin complex in laryngeal squamous cell carcinoma.

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9.  Transoral treatment strategies for head and neck tumors.

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10.  Management of locally advanced laryngeal cancer.

Authors:  Alexander D Karatzanis; Georgios Psychogios; Frank Waldfahrer; Markus Kapsreiter; Johannes Zenk; George A Velegrakis; Heinrich Iro
Journal:  J Otolaryngol Head Neck Surg       Date:  2014-01-28
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