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Literature DB >> 19568669

Self-powered microfluidic chips for multiplexed protein assays from whole blood.

Lidong Qin¹, Ophir Vermesh, Qihui Shi, James R Heath.

Abstract

We report herein on a self-powered, self-contained microfluidic-based chip designed to separate plasma from whole blood, and then execute an assay of a multiplexed panel of plasma biomarker proteins. The power source is based upon a chemical reaction that is catalytically triggered by the push of a button on the chip. We demonstrate assays of a dozen blood-based protein biomarkers using this automated, self-contained device. This platform can potentially permit high throughput, accurate, multiplexed blood diagnostic measurements in remote locations and by minimally trained individuals.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19568669 PMCID： PMC3651861 DOI： 10.1039/b821247c

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

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