BACKGROUND: Delirium is an important problem especially in older medical inpatients. OBJECTIVE: The authors asked whether delirium and its duration are associated with higher mortality in a 3-month follow-up period. METHOD: In this prospective cohort study, inpatients age 65 and older were assessed every 48 hours with the Confusion Assessment Method. RESULTS: Of 542 patients enrolled, 192 (35.4%) developed delirium. After 3 months, mortality in the delirium cohort was 25.9%, and in the nondelirium cohort was 5.8%. Delirium was independently associated with mortality, and increased by 11% for every 48 hours of delirium. CONCLUSION: Delirium and increased delirium durations are significantly associated with higher mortality.
BACKGROUND:Delirium is an important problem especially in older medical inpatients. OBJECTIVE: The authors asked whether delirium and its duration are associated with higher mortality in a 3-month follow-up period. METHOD: In this prospective cohort study, inpatients age 65 and older were assessed every 48 hours with the Confusion Assessment Method. RESULTS: Of 542 patients enrolled, 192 (35.4%) developed delirium. After 3 months, mortality in the delirium cohort was 25.9%, and in the nondelirium cohort was 5.8%. Delirium was independently associated with mortality, and increased by 11% for every 48 hours of delirium. CONCLUSION:Delirium and increased delirium durations are significantly associated with higher mortality.
Authors: Gen Shinozaki; Nicholas L Bormann; Aubrey C Chan; Kasra Zarei; Nicholas A Sparr; Mason J Klisares; Sydney S Jellison; Jonathan T Heinzman; Elijah B Dahlstrom; Gabrielle N Duncan; Lindsey N Gaul; Robert J Wanzek; Ellyn M Cramer; Charlotte G Wimmel; Sayeh Sabbagh; Kumi Yuki; Michelle T Weckmann; Thoru Yamada; Matthew D Karam; Nicolas O Noiseux; Eri Shinozaki; Hyunkeun R Cho; Sangil Lee; John W Cromwell Journal: J Clin Psychiatry Date: 2019-09-03 Impact factor: 4.384
Authors: Allan Gottschalk; Jessica Hubbs; Ami R Vikani; Lindsey B Gottschalk; Frederick E Sieber Journal: Anesth Analg Date: 2015-11 Impact factor: 5.108
Authors: Jin H Han; Alex Chen; Eduard E Vasilevskis; John F Schnelle; E Wesley Ely; Rameela Chandrasekhar; Ryan D Morrison; Timothy P Ryan; J Scott Daniels; Jeff J Sutherland; Sandra F Simmons Journal: J Am Geriatr Soc Date: 2019-09-10 Impact factor: 5.562
Authors: Daniel James Ryan; Niamh Annmarie O'Regan; Ronán Ó Caoimh; Josie Clare; Marie O'Connor; Maeve Leonard; John McFarland; Sheila Tighe; Kathleen O'Sullivan; Paula T Trzepacz; David Meagher; Suzanne Timmons Journal: BMJ Open Date: 2013-01-07 Impact factor: 2.692
Authors: Chantal J Slor; Joost Witlox; Dimitrios Adamis; David J Meagher; Tjeerd van der Ploeg; Rene W M M Jansen; Mireille F M van Stijn; Alexander P J Houdijk; Willem A van Gool; Piet Eikelenboom; Jos F M de Jonghe Journal: Curr Gerontol Geriatr Res Date: 2013-02-27