Literature DB >> 19567758

Neuropsychiatric problems after traumatic brain injury: unraveling the silent epidemic.

Sandeep Vaishnavi1, Vani Rao, Jesse R Fann.   

Abstract

BACKGROUND: Traumatic brain injury (TBI) is a significant public health concern. According to the Centers for Disease Control and Prevention, about 1.4 million people in the United States sustain a TBI annually.
OBJECTIVE: This review places particular emphasis on the current knowledge of effective treatment of TBI symptoms, and proposes directions for future research.
RESULTS: Neuropsychiatric problems are more prevalent and longer-lasting in TBI patients than in the general population. About 40% of TBI victims suffer from two or more psychiatric disorders, and a similar percentage experience at least one unmet need for cognitive, emotional, or job assistance 1 year after injury. The entire spectrum of TBI severity, from mild to severe, is associated with an increase in psychiatric conditions.
CONCLUSION: Despite the high incidence of severe consequences of TBI, there are scarce empirical data to guide psychiatric treatment. Some approaches that have been helpful include cognitive and behavioral therapy and pharmacologic treatment. The authors list specific research recommendations that could further identify useful therapeutic interventions.

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Year:  2009        PMID: 19567758     DOI: 10.1176/appi.psy.50.3.198

Source DB:  PubMed          Journal:  Psychosomatics        ISSN: 0033-3182            Impact factor:   2.386


  53 in total

Review 1.  Effects of psychological and biomechanical trauma on brain and behavior.

Authors:  Thomas W McAllister; Murray B Stein
Journal:  Ann N Y Acad Sci       Date:  2010-10       Impact factor: 5.691

Review 2.  Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies.

Authors:  Jennifer L McGuire; Laura B Ngwenya; Robert E McCullumsmith
Journal:  Mol Psychiatry       Date:  2018-09-13       Impact factor: 15.992

3.  Frontal brain injury chronically impairs timing behavior in rats.

Authors:  Taylor L Scott; Cole Vonder Haar
Journal:  Behav Brain Res       Date:  2018-09-10       Impact factor: 3.332

Review 4.  Elucidating opportunities and pitfalls in the treatment of experimental traumatic brain injury to optimize and facilitate clinical translation.

Authors:  Patricia B de la Tremblaye; Darik A O'Neil; Megan J LaPorte; Jeffrey P Cheng; Joshua A Beitchman; Theresa Currier Thomas; Corina O Bondi; Anthony E Kline
Journal:  Neurosci Biobehav Rev       Date:  2017-05-30       Impact factor: 8.989

5.  Distinct effect of impact rise times on immediate and early neuropathology after brain injury in juvenile rats.

Authors:  Eric J Neuberger; Radia Abdul Wahab; Archana Jayakumar; Bryan J Pfister; Vijayalakshmi Santhakumar
Journal:  J Neurosci Res       Date:  2014-05-05       Impact factor: 4.164

6.  Acute neuroimmune modulation attenuates the development of anxiety-like freezing behavior in an animal model of traumatic brain injury.

Authors:  Krista M Rodgers; Florencia M Bercum; Danielle L McCallum; Jerry W Rudy; Lauren C Frey; Kirk W Johnson; Linda R Watkins; Daniel S Barth
Journal:  J Neurotrauma       Date:  2012-04-26       Impact factor: 5.269

7.  Neuropsychiatric symptoms and the use of complementary and alternative medicine.

Authors:  Maulik P Purohit; Rebecca Erwin Wells; Ross D Zafonte; Roger B Davis; Russell S Phillips
Journal:  PM R       Date:  2012-10-24       Impact factor: 2.298

8.  Reversal of established traumatic brain injury-induced, anxiety-like behavior in rats after delayed, post-injury neuroimmune suppression.

Authors:  Krista M Rodgers; Yuetiva K Deming; Florencia M Bercum; Serhiy Y Chumachenko; Julie L Wieseler; Kirk W Johnson; Linda R Watkins; Daniel S Barth
Journal:  J Neurotrauma       Date:  2013-11-20       Impact factor: 5.269

9.  Treadmill exercise protects against pentylenetetrazol-induced seizures and oxidative stress after traumatic brain injury.

Authors:  Luiz Fernando Almeida Silva; Maurício Scopel Hoffmann; Rogério da Rosa Gerbatin; Fernando da Silva Fiorin; Fernando Dobrachinski; Bibiana Castagna Mota; Angelica Terezinha Barth Wouters; Saulo Petinatti Pavarini; Félix Alexandre Antunes Soares; Michele Rechia Fighera; Luiz Fernando Freire Royes
Journal:  J Neurotrauma       Date:  2013-07-15       Impact factor: 5.269

10.  Cortisol Supplement Combined with Psychotherapy and Citalopram Improves Depression Outcomes in Patients with Hypocortisolism after Traumatic Brain Injury.

Authors:  Lanlan Luo; Yan Chai; Rongcai Jiang; Xin Chen; Tao Yan
Journal:  Aging Dis       Date:  2015-11-17       Impact factor: 6.745

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