| Literature DB >> 19566795 |
K S Eriksson1, O A Sergeeva, H L Haas, O Selbach.
Abstract
Orexin/hypocretin neurones in the posterior hypothalamus are mutually connected with noradrenergic, serotonergic, dopaminergic, histaminergic, and cholinergic neurone systems. They activate these targets by direct post-synaptic and indirect pre-synaptic mechanisms and in turn receive inhibitory feedback and excitatory feed forward control. With respect to behavioural state control, orexin/hypocretin neurones are conducting the orchestra of biogenic amines. This review highlights the role of these players in the control of energy administration, sleep-wake architecture, cortical activation, plasticity, and memory functions in health and disease.Entities:
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Year: 2009 PMID: 19566795 DOI: 10.1111/j.1748-1716.2009.02015.x
Source DB: PubMed Journal: Acta Physiol (Oxf) ISSN: 1748-1708 Impact factor: 6.311