Literature DB >> 19566795

Orexins/hypocretins and aminergic systems.

K S Eriksson1, O A Sergeeva, H L Haas, O Selbach.   

Abstract

Orexin/hypocretin neurones in the posterior hypothalamus are mutually connected with noradrenergic, serotonergic, dopaminergic, histaminergic, and cholinergic neurone systems. They activate these targets by direct post-synaptic and indirect pre-synaptic mechanisms and in turn receive inhibitory feedback and excitatory feed forward control. With respect to behavioural state control, orexin/hypocretin neurones are conducting the orchestra of biogenic amines. This review highlights the role of these players in the control of energy administration, sleep-wake architecture, cortical activation, plasticity, and memory functions in health and disease.

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Year:  2009        PMID: 19566795     DOI: 10.1111/j.1748-1716.2009.02015.x

Source DB:  PubMed          Journal:  Acta Physiol (Oxf)        ISSN: 1748-1708            Impact factor:   6.311


  12 in total

1.  Differential effects of a dual orexin receptor antagonist (SB-649868) and zolpidem on sleep initiation and consolidation, SWS, REM sleep, and EEG power spectra in a model of situational insomnia.

Authors:  Paolo Bettica; Lisa Squassante; John A Groeger; Brian Gennery; Raphaelle Winsky-Sommerer; Derk-Jan Dijk
Journal:  Neuropsychopharmacology       Date:  2012-01-11       Impact factor: 7.853

2.  Orexins excite neurons of the rat cerebellar nucleus interpositus via orexin 2 receptors in vitro.

Authors:  Lei Yu; Xiao-Yang Zhang; Jun Zhang; Jing-Ning Zhu; Jian-Jun Wang
Journal:  Cerebellum       Date:  2010-03       Impact factor: 3.847

3.  Hypocretin/orexin neurons contribute to hippocampus-dependent social memory and synaptic plasticity in mice.

Authors:  Liya Yang; Bende Zou; Xiaoxing Xiong; Conrado Pascual; James Xie; Adam Malik; Julian Xie; Takeshi Sakurai; Xinmin Simon Xie
Journal:  J Neurosci       Date:  2013-03-20       Impact factor: 6.167

Review 4.  The waking brain: an update.

Authors:  Jian-Sheng Lin; Christelle Anaclet; Olga A Sergeeva; Helmut L Haas
Journal:  Cell Mol Life Sci       Date:  2011-02-13       Impact factor: 9.261

5.  Orexin receptor antagonism, a new sleep-enabling paradigm: a proof-of-concept clinical trial.

Authors:  P Hoever; G Dorffner; H Beneš; T Penzel; H Danker-Hopfe; M J Barbanoj; G Pillar; B Saletu; O Polo; D Kunz; J Zeitlhofer; S Berg; M Partinen; C L Bassetti; B Högl; I O Ebrahim; E Holsboer-Trachsler; H Bengtsson; Y Peker; U-M Hemmeter; E Chiossi; G Hajak; J Dingemanse
Journal:  Clin Pharmacol Ther       Date:  2012-06       Impact factor: 6.875

6.  CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis.

Authors:  Chul-Hyun Cho; Heon-Jeong Lee; Hyun Goo Woo; Ji-Hye Choi; Tiffany A Greenwood; John R Kelsoe
Journal:  Psychiatry Investig       Date:  2015-07-06       Impact factor: 2.505

Review 7.  Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far.

Authors:  Africa Flores; Rafael Maldonado; Fernando Berrendero
Journal:  Front Neurosci       Date:  2013-12-20       Impact factor: 4.677

8.  Acute suppressive and long-term phase modulation actions of orexin on the mammalian circadian clock.

Authors:  Mino D C Belle; Alun T L Hughes; David A Bechtold; Peter Cunningham; Massimo Pierucci; Denis Burdakov; Hugh D Piggins
Journal:  J Neurosci       Date:  2014-03-05       Impact factor: 6.167

9.  Different levels in orexin concentrations and risk factors associated with higher orexin levels: comparison between detoxified opiate and methamphetamine addicts in 5 Chinese cities.

Authors:  Haoran Zhang; Zhi Lian; Shiyan Yan; Yanping Bao; Zhimin Liu
Journal:  Biomed Res Int       Date:  2013-09-12       Impact factor: 3.411

Review 10.  Mechanisms of body weight fluctuations in Parkinson's disease.

Authors:  Andrea Kistner; Eugénie Lhommée; Paul Krack
Journal:  Front Neurol       Date:  2014-06-02       Impact factor: 4.003

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