Literature DB >> 19566671

Blocking of fetal K antigens on cord red blood cells by maternal anti-K.

E Lee1, M Redman, I Owen.   

Abstract

A 26-year-old Caucasian female in her second pregnancy grouped as A, D+ R(1)R(1) K- with anti-K (titre: 256) at booking. Her partner was typed as K1 positive. Baby was born with Hb 23.1 g/dl. Cord samples were referred to our laboratory for investigation and were found to be DAT 5+, IgG and anti-K was eluted from the red cells. Cord samples typed as A, R(1)r K- by DiaMed DiaClon Rh subgroups & K card. We report a case of false negative K1 phenotyping due to blocking with maternal anti-K.

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Year:  2009        PMID: 19566671     DOI: 10.1111/j.1365-3148.2009.00917.x

Source DB:  PubMed          Journal:  Transfus Med        ISSN: 0958-7578            Impact factor:   2.019


  4 in total

1.  Blocking phenomenon occurs with murine monoclonal antibodies (anti-Fy(a)) in a neonate with a positive direct antiglobulin test due to maternal anti-Fy(a).

Authors:  Edmond Lee; Carol Cantwell; Kehinde O Muyibi; Rekha Modasia; Megan Rowley; Helen New
Journal:  Blood Transfus       Date:  2015-01-30       Impact factor: 3.443

2.  RhD blocking phenomenon implicated in an immunohaematological diagnostic dilemma in a case of RhD-haemolytic disease of the foetus.

Authors:  Anupam Verma; Deepti Sachan; Archana Bajpayee; Priti Elhence; Anju Dubey; Mandakini Pradhan
Journal:  Blood Transfus       Date:  2012-07-04       Impact factor: 3.443

3.  Blocked D phenomenon.

Authors:  Edmond Lee
Journal:  Blood Transfus       Date:  2012-07-04       Impact factor: 3.443

4.  K-antigen blocking in a case of haemolytic disease of the foetus and newborn.

Authors:  Silvia Manfroi; Claudio Velati
Journal:  Blood Transfus       Date:  2017-10       Impact factor: 5.752

  4 in total

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