Literature DB >> 19566359

An overview of heel Marjolin's ulcers in the Orthopedic Department of Urmia University of Medical Sciences.

Ahmad Shahla1.   

Abstract

Marjolin's ulcer is defined as a malignant, ulcerating neoplasm occurring in cicatricial tissues. The cancer is usually a well-differentiated squamous cell carcinoma. Wide resection is complicated with a recurrence rate of 20% to 50% and a metastasis rate of 54%. Therefore, we chose amputation as the modality of treatment for heel Marjolin's ulcers in Urmia and presented their results in this study.During the last 10 years in Urmia, nineteen cases of heel Marjolin's ulcers has been detected. About 47% were due to childhood burn. Malignancy was mainly squamous cell carcinoma. The mean latent period of malignant transformation was 11 years. All cases were treated with amputation, without any recurrence or metastasis in an average four-year follow-up period.The squamous cell carcinoma of Marjolin's ulcer has the worst prognosis in comparison with other squamous cell carcinomas and it requires an aggressive treatment.

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Year:  2009        PMID: 19566359

Source DB:  PubMed          Journal:  Arch Iran Med        ISSN: 1029-2977            Impact factor:   1.354


  8 in total

1.  Ten years of experience in chronic ulcers and malignant transformation.

Authors:  Maria G Onesti; Pasquale Fino; Paolo Fioramonti; Vittoria Amorosi; Nicolò Scuderi
Journal:  Int Wound J       Date:  2013-07-19       Impact factor: 3.315

2.  Clinicopathologic Characteristics and Prognosis Analysis of Marjolin's Ulcer in 40 Cases.

Authors:  Bi-Wei Guo; Teng Pan; Hong-Bo Chen; Li Zhu; Meng Tian; Jie-Cong Wang; Xiao-Dan Li
Journal:  Curr Med Sci       Date:  2018-12-07

3.  An odd very early marjolin's ulcer after minimal hand burn.

Authors:  A A Mohammadi; A Foroutan; S Mohammadi; M H Anbardar
Journal:  Ann Burns Fire Disasters       Date:  2017-09-30

4.  A Comprehensive Review on Marjolin's Ulcers: Diagnosis and Treatment.

Authors:  Brian Pekarek; Stacie Buck; Lawrence Osher
Journal:  J Am Col Certif Wound Spec       Date:  2011-09

5.  A Retrospective Study of Marjolin's Ulcer Over an Eleven Year Period.

Authors:  Vasu Reddy Challa; Vijayalakshmi Deshmane; Madhusudana Bommasandra Ashwatha Reddy
Journal:  J Cutan Aesthet Surg       Date:  2014-07

6.  Early Marjolin's Ulcer after Minimal Superficial Burn.

Authors:  Ali Akbar Mohammadi; Seyed Morteza Seyed Jafari; Masoud Hosseinzadeh
Journal:  Iran J Med Sci       Date:  2013-03

7.  A Rare Case of Aggressive Digital Adenocarcinoma of the Lower Extremity, Masquerading as an Ulcerative Lesion that Clinically Favored Benignancy.

Authors:  Ryan Vazales; Dustin Constant; Robert J Snyder
Journal:  Healthcare (Basel)       Date:  2014-08-27

8.  Systematic Review of Modern Case Series of Squamous Cell Cancer Arising in a Chronic Ulcer (Marjolin's Ulcer) of the Skin.

Authors:  Mohamed A Abdi; Michael Yan; Timothy P Hanna
Journal:  JCO Glob Oncol       Date:  2020-06
  8 in total

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