Literature DB >> 19561783

Hepatic focal nodular hyperplasia: when a benign lesion becomes "malignant". Report of a case.

V Papanikolaou1, D Vrochides, P Margari, D Giakoustidis, N Antoniadis, K Tsinoglou, E Akriviadis, D Takoudas.   

Abstract

In a 34 year-old woman complaining of right upper quadrant pain and having mildly elevated total bilirubin, the imaging investigation revealed a liver lesion with characteristics of focal nodular hyperplasia, measuring 3.8 cm, at the confluence of the hepatic veins. The mass was obstructing the left and middle hepatic veins and nearly obstructing the right hepatic vein. Dilation of the splenic vein with development of retropancreatic varices, splenomegaly and free abdominal fluid were also present. The patient underwent an uncomplicated left hemihepatectomy. Patients postoperative total bilirubin was normalized. Tomographic imaging three months after the liver resection revealed resolution of all the Budd-Chiari radiographic signs. This is a report of a case where a hepatic focal nodular hyperplasia, despite its benign nature, required extensive and urgent surgical intervention due to its location and potential dangers secondary to the development of portal hypertension.

Entities:  

Keywords:  Budd-Chiari; focal nodular hyperplasia; liver resection; portal hypertension

Year:  2009        PMID: 19561783      PMCID: PMC2683454     

Source DB:  PubMed          Journal:  Hippokratia        ISSN: 1108-4189            Impact factor:   0.471


  4 in total

Review 1.  [Benign liver tumors].

Authors:  D Cherqui
Journal:  J Chir (Paris)       Date:  2001-02

2.  Benign and solid tumors of the liver: relationship to sex, age, size of tumors, and outcome.

Authors:  K R Reddy; S Kligerman; J Levi; A Livingstone; E Molina; D Franceschi; S Badalamenti; L Jeffers; A Tzakis; E R Schiff
Journal:  Am Surg       Date:  2001-02       Impact factor: 0.688

3.  Hepatocellular carcinoma with a central scar and a scalloped tumor margin resembling focal nodular hyperplasia in macroscopic appearance.

Authors:  Masakazu Yamamoto; Shyunichi Ariizumi; Kenji Yoshitoshi; Akiko Saito; Masayuki Nakano; Ken Takasaki
Journal:  J Surg Oncol       Date:  2006-12-01       Impact factor: 3.454

4.  Arterial and portal circulation and parenchymal changes in Budd-Chiari syndrome: a study in 17 explanted livers.

Authors:  Dominique Cazals-Hatem; Valérie Vilgrain; Pascal Genin; Marie-Hélène Denninger; François Durand; Jacques Belghiti; Dominique Valla; Claude Degott
Journal:  Hepatology       Date:  2003-03       Impact factor: 17.425

  4 in total
  1 in total

1.  Giant focal nodular hyperplasia determining Budd-Chiari syndrome: an operative challenge requiring 210 min of liver ischemia.

Authors:  Felice Giuliante; Francesco Ardito; Giuseppina Ranucci; Ivo Giovannini; Gennaro Nuzzo
Journal:  Updates Surg       Date:  2011-09-16
  1 in total

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