| Literature DB >> 19560576 |
Emily J Swindle1, Jane E Collins, Donna E Davies.
Abstract
The bronchial epithelium is pivotally involved in the provision of chemical, physical, and immunologic barriers to the inhaled environment. These barriers serve to maintain normal homeostasis, but when compromised, the immunologic barrier becomes activated to protect the internal milieu of the lung. We discuss what is currently understood about abnormalities in these barrier functions in patients with asthma and consider novel therapeutic opportunities that target this key structure.Entities:
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Year: 2009 PMID： 19560576 DOI： 10.1016/j.jaci.2009.05.037
Source DB: PubMed Journal: J Allergy Clin Immunol ISSN： 0091-6749 Impact factor: 10.793