| Literature DB >> 19559610 |
Hiroyuki Takei1, Masafumi Kurosumi, Takashi Yoshida, Jun Ninomiya, Yuko Ishikawa, Yuji Hayashi, Katsunori Tozuka, Hideki Asakawa, Hanako Oba, Kenichi Inoue, Toshio Tabei.
Abstract
It remains to be clarified whether a positive sentinel lymph node biopsy (SLNB) can predict the number of metastatic axillary nodes. This study examined a consecutive series of women with unilateral invasive breast cancer who underwent axillary lymph node dissection after an intra-operative positive SLNB. The numbers of positive and negative sentinel lymph nodes (SLNs) were analyzed for a likelihood of pN1a, pN2a, and pN3a diseases as per the UICC TNM classification. Of the 368 study patients, 165 (45%) had one positive SLN and one or more negative SLNs. This result represented the most common combination of positive and negative SLNs. It was also the most predictive indicator (93%) of pN1a disease and the least predictive indicator (7% or 0%) of pN2a or pN3a disease, respectively. The numbers of positive and negative SLNs can predict the number of metastatic axillary nodes in breast cancer patients.Entities:
Mesh：
Year: 2009 PMID： 19559610 DOI： 10.1016/j.breast.2009.05.007
Source DB: PubMed Journal: Breast ISSN： 0960-9776 Impact factor: 4.380