Literature DB >> 19557954

Mustard gas or sulfur mustard: an old chemical agent as a new terrorist threat.

Monica Wattana1, Tareg Bey.   

Abstract

Sulfur mustard is a member of the vesicant class of chemical warfare agents that causes blistering to the skin and mucous membranes. There is no specific antidote, and treatment consists of systematically alleviating symptoms. Historically, sulfur mustard was used extensively in inter-governmental conflicts within the trenches of Belgium and France during World War I and during the Iran-Iraq conflict. Longitudinal studies of exposed victims show that sulfur mustard causes long-term effects leading to high morbidity. Given that only a small amount of sulfur mustard is necessary to potentially cause an enormous number of casualties, disaster-planning protocol necessitates the education and training of first-line healthcare responders in the recognition, decontamination, triage, and treatment of sulfur mustard-exposed victims in a large-scale scenario.

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Year:  2009        PMID: 19557954     DOI: 10.1017/s1049023x0000649x

Source DB:  PubMed          Journal:  Prehosp Disaster Med        ISSN: 1049-023X            Impact factor:   2.040


  31 in total

1.  Doxycycline hydrogels as a potential therapy for ocular vesicant injury.

Authors:  Marion K Gordon; Andrea Desantis; Manjeet Deshmukh; Carl Jeffrey Lacey; Rita A Hahn; John Beloni; Sivanaga S Anumolu; John J Schlager; Michael A Gallo; Donald R Gerecke; Ned D Heindel; Kathy K H Svoboda; Michael C Babin; Patrick J Sinko
Journal:  J Ocul Pharmacol Ther       Date:  2010-10       Impact factor: 2.671

2.  Acute corneal injury in rabbits following nitrogen mustard ocular exposure.

Authors:  Dinesh G Goswami; Rama Kant; David A Ammar; Dileep Kumar; Robert W Enzenauer; J Mark Petrash; Neera Tewari-Singh; Rajesh Agarwal
Journal:  Exp Mol Pathol       Date:  2019-06-21       Impact factor: 3.362

3.  Time course of lesion development in the hairless guinea-pig model of sulfur mustard-induced dermal injury.

Authors:  Janet M Benson; JeanClare Seagrave; Waylon M Weber; Colleen D Santistevan; Gary R Grotendorst; Gregory S Schultz; Thomas H March
Journal:  Wound Repair Regen       Date:  2011-03-16       Impact factor: 3.617

4.  Dynamic cytotoxic profiles of sulfur mustard in human dermal cells determined by multiparametric high-content analysis.

Authors:  Long Long; Wei Li; Wei Chen; Fei-Fei Li; Hua Li; Li-Li Wang
Journal:  Toxicol Res (Camb)       Date:  2016-01-11       Impact factor: 3.524

5.  Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog.

Authors:  Marie Roser; David Béal; Camille Eldin; Leslie Gudimard; Fanny Caffin; Fanny Gros-Désormeaux; Daniel Léonço; François Fenaille; Christophe Junot; Christophe Piérard; Thierry Douki
Journal:  Anal Bioanal Chem       Date:  2021-01-07       Impact factor: 4.142

6.  Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard.

Authors:  Jeffrey D Laskin; Gabriella Wahler; Claire R Croutch; Patrick J Sinko; Debra L Laskin; Diane E Heck; Laurie B Joseph
Journal:  Exp Mol Pathol       Date:  2020-05-21       Impact factor: 3.362

7.  TRPA1 and CGRP antagonists counteract vesicant-induced skin injury and inflammation.

Authors:  Satyanarayana Achanta; Narendranath Reddy Chintagari; Marian Brackmann; Shrilatha Balakrishna; Sven-Eric Jordt
Journal:  Toxicol Lett       Date:  2018-03-10       Impact factor: 4.372

8.  Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure.

Authors:  Matthew D McGraw; So-Young Kim; Carl W White; Livia A Veress
Journal:  Ann N Y Acad Sci       Date:  2020-05-14       Impact factor: 5.691

9.  Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease.

Authors:  Davood Attaran; Shahrzad M Lari; Mohammad Towhidi; Hassan Ghobadi Marallu; Hossein Ayatollahi; Mohammad Khajehdaluee; Mostafa Ghanei; Reza Basiri
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2010-10-05

10.  Mustard vesicants alter expression of the endocannabinoid system in mouse skin.

Authors:  Irene M Wohlman; Gabriella M Composto; Diane E Heck; Ned D Heindel; C Jeffrey Lacey; Christophe D Guillon; Robert P Casillas; Claire R Croutch; Donald R Gerecke; Debra L Laskin; Laurie B Joseph; Jeffrey D Laskin
Journal:  Toxicol Appl Pharmacol       Date:  2016-04-26       Impact factor: 4.219

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