| Literature DB >> 19557361 |
Wonsik Jeong1, Seong Su Hong, Nahyun Kim, Young Taek Yang, Yu Su Shin, Chul Lee, Bang Yeon Hwang, Dongho Lee.
Abstract
A new triterpenoid, 30-hydroxyalphitolic acid 1, and eight known triterpenoids, alphitolic acid 2, lupenol 3, 3-acetoxy-olean-18-en-28-oic acid 4, betulinic acid 5, ursolic acid 6, betulinic acid 3-O-caffeate 7, morolic acid 3-O-caffeate 8, and ursolic acid 3-O-caffeate 9, were isolated from Callistemon lanceolatus. Their structures were determined using spectroscopic techniques, which included 1D- and 2D-NMR. All compounds were evaluated for the inhibition of LPS-induced nitric oxide production in murine macrophage RAW264.7 cells. Betulinic acid 3-O-caffeate 7 showed a moderate inhibitory effect on nitric oxide production with IC(50) value of 15.4 microM.Entities:
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Year: 2009 PMID： 19557361 DOI： 10.1007/s12272-009-1605-3
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946