Literature DB >> 19557351

Nup211, the fission yeast homolog of Mlp1/Tpr, is involved in mRNA export.

Jin-Ah Bae1, Donggerami Moon, Jin Ho Yoon.   

Abstract

Synthetic lethal mutants have been previously isolated in fission yeast Schizosaccharomyces pombe, which genetically interact with spmex67, in order to identify the genes involved in mRNA export. The nup211 gene was isolated by complementation of the growth defect in one of the synthetic lethal mutants, SLMex2, under synthetic lethal condition. We showed that Nup211, fission yeast homolog of Mlpl/Mlp2/Tpr, is essential for vegetative growth and Nup211-GFP proteins expressed at endogenous level are localized mainly in nuclear periphery. The accumulation of poly(A)(+) RNA in the nucleus is exhibited when expression of nup211 is repressed or over-expressed. These results suggest that the Nup211 protein plays a pivotal role of mRNA export in fission yeast.

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Year:  2009        PMID： 19557351     DOI： 10.1007/s12275-009-0125-7

Source DB:  PubMed          Journal:  J Microbiol        ISSN： 1225-8873            Impact factor:   3.422


  41 in total

1.  Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export.

Authors:  K Strässer; E Hurt
Journal:  EMBO J       Date:  2000-02-01       Impact factor: 11.598

Review 2.  Nuclear export of mRNA: from the site of transcription to the cytoplasm.

Authors:  Judith A Erkmann; Ulrike Kutay
Journal:  Exp Cell Res       Date:  2004-05-15       Impact factor: 3.905

Review 3.  Dynamic nuclear pore complexes: life on the edge.

Authors:  Elizabeth J Tran; Susan R Wente
Journal:  Cell       Date:  2006-06-16       Impact factor: 41.582

4.  Mlp2p, a component of nuclear pore attached intranuclear filaments, associates with nic96p.

Authors:  B Kosova; N Panté; C Rollenhagen; A Podtelejnikov; M Mann; U Aebi; E Hurt
Journal:  J Biol Chem       Date:  2000-01-07       Impact factor: 5.157

5.  Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p.

Authors:  Deanna M Green; Kavita A Marfatia; Emily B Crafton; Xing Zhang; Xiaodong Cheng; Anita H Corbett
Journal:  J Biol Chem       Date:  2002-01-04       Impact factor: 5.157

6.  Elf1p, a member of the ABC class of ATPases, functions as a mRNA export factor in Schizosacchromyces pombe.

Authors:  Libor Kozak; Ganesh Gopal; Jin Ho Yoon; Zuben E Sauna; Suresh V Ambudkar; Anjan G Thakurta; Ravi Dhar
Journal:  J Biol Chem       Date:  2002-07-10       Impact factor: 5.157

7.  TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus.

Authors:  P Grüter; C Tabernero; C von Kobbe; C Schmitt; C Saavedra; A Bachi; M Wilm; B K Felber; E Izaurralde
Journal:  Mol Cell       Date:  1998-04       Impact factor: 17.970

8.  Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex.

Authors:  Manuela E Hase; Volker C Cordes
Journal:  Mol Biol Cell       Date:  2003-05       Impact factor: 4.138

9.  The nuclear pore complex-associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly.

Authors:  Mario Niepel; Caterina Strambio-de-Castillia; Joseph Fasolo; Brian T Chait; Michael P Rout
Journal:  J Cell Biol       Date:  2005-07-18       Impact factor: 10.539

10.  Proteins connecting the nuclear pore complex with the nuclear interior.

Authors:  C Strambio-de-Castillia; G Blobel; M P Rout
Journal:  J Cell Biol       Date:  1999-03-08       Impact factor: 10.539
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  6 in total

Review 1.  Double duty for nuclear proteins--the price of more open forms of mitosis.

Authors:  Colin P De Souza; Stephen A Osmani
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2.  Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe.

Authors:  Haruhiko Asakawa; Hui-Ju Yang; Takaharu G Yamamoto; Chizuru Ohtsuki; Yuji Chikashige; Kumiko Sakata-Sogawa; Makio Tokunaga; Masaaki Iwamoto; Yasushi Hiraoka; Tokuko Haraguchi
Journal:  Nucleus       Date:  2014-03-12       Impact factor: 4.197

3.  Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast.

Authors:  Haruhiko Asakawa; Tomoko Kojidani; Hui-Ju Yang; Chizuru Ohtsuki; Hiroko Osakada; Atsushi Matsuda; Masaaki Iwamoto; Yuji Chikashige; Koji Nagao; Chikashi Obuse; Yasushi Hiraoka; Tokuko Haraguchi
Journal:  PLoS Genet       Date:  2019-06-06       Impact factor: 5.917

4.  Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe.

Authors:  Joseph M Varberg; Jay R Unruh; Andrew J Bestul; Azqa A Khan; Sue L Jaspersen
Journal:  Life Sci Alliance       Date:  2022-03-30

5.  Tts1, the fission yeast homologue of the TMEM33 family, functions in NE remodeling during mitosis.

Authors:  Dan Zhang; Snezhana Oliferenko
Journal:  Mol Biol Cell       Date:  2014-08-07       Impact factor: 4.138

6.  The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.

Authors:  Silvia Salas-Pino; Paola Gallardo; Ramón R Barrales; Sigurd Braun; Rafael R Daga
Journal:  J Cell Biol       Date:  2017-10-03       Impact factor: 10.539
  6 in total

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