Literature DB >> 19557079

Tumors line up for a letdown.

Joshua T Mendell1.   

Abstract

MicroRNAs (miRNAs) and the pathways that regulate their expression have critical functions during normal development. A new study demonstrates that select cancer cells have appropriated one developmental mechanism of miRNA regulation, the inhibition of let-7 biogenesis by the Lin-28 and Lin-28B RNA binding proteins, to rid themselves of an antitumorigenic miRNA.

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Year:  2009        PMID： 19557079     DOI： 10.1038/ng0709-768

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  14 in total

1.  The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans.

Authors:  B J Reinhart; F J Slack; M Basson; A E Pasquinelli; J C Bettinger; A E Rougvie; H R Horvitz; G Ruvkun
Journal:  Nature       Date:  2000-02-24       Impact factor: 49.962

2.  Extensive post-transcriptional regulation of microRNAs and its implications for cancer.

Authors:  J Michael Thomson; Martin Newman; Joel S Parker; Elizabeth M Morin-Kensicki; Tricia Wright; Scott M Hammond
Journal:  Genes Dev       Date:  2006-08-01       Impact factor: 11.361

3.  MicroRNA expression profiles classify human cancers.

Authors:  Jun Lu; Gad Getz; Eric A Miska; Ezequiel Alvarez-Saavedra; Justin Lamb; David Peck; Alejandro Sweet-Cordero; Benjamin L Ebert; Raymond H Mak; Adolfo A Ferrando; James R Downing; Tyler Jacks; H Robert Horvitz; Todd R Golub
Journal:  Nature       Date:  2005-06-09       Impact factor: 49.962

4.  Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing.

Authors:  Martin A Newman; J Michael Thomson; Scott M Hammond
Journal:  RNA       Date:  2008-06-19       Impact factor: 4.942

5.  Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation.

Authors:  Tsung-Cheng Chang; Lauren R Zeitels; Hun-Way Hwang; Raghu R Chivukula; Erik A Wentzel; Michael Dews; Jason Jung; Ping Gao; Chi V Dang; Michael A Beer; Andrei Thomas-Tikhonenko; Joshua T Mendell
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-11       Impact factor: 11.205

6.  A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.

Authors:  Agnieszka Rybak; Heiko Fuchs; Lena Smirnova; Christine Brandt; Elena E Pohl; Robert Nitsch; F Gregory Wulczyn
Journal:  Nat Cell Biol       Date:  2008-07-06       Impact factor: 28.824

Review 7.  An elegant miRror: microRNAs in stem cells, developmental timing and cancer.

Authors:  Rachael A Nimmo; Frank J Slack
Journal:  Chromosoma       Date:  2009-04-03       Impact factor: 4.316

8.  Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7.

Authors:  Surabhi Dangi-Garimella; Jieun Yun; Eva M Eves; Martin Newman; Stefan J Erkeland; Scott M Hammond; Andy J Minn; Marsha Rich Rosner
Journal:  EMBO J       Date:  2009-01-15       Impact factor: 11.598

9.  Lin28 promotes transformation and is associated with advanced human malignancies.

Authors:  Srinivas R Viswanathan; John T Powers; William Einhorn; Yujin Hoshida; Tony L Ng; Sara Toffanin; Maureen O'Sullivan; Jun Lu; Letha A Phillips; Victoria L Lockhart; Samar P Shah; Pradeep S Tanwar; Craig H Mermel; Rameen Beroukhim; Mohammad Azam; Jose Teixeira; Matthew Meyerson; Timothy P Hughes; Josep M Llovet; Jerald Radich; Charles G Mullighan; Todd R Golub; Poul H Sorensen; George Q Daley
Journal:  Nat Genet       Date:  2009-05-31       Impact factor: 38.330

10.  Selective blockade of microRNA processing by Lin28.

Authors:  Srinivas R Viswanathan; George Q Daley; Richard I Gregory
Journal:  Science       Date:  2008-02-21       Impact factor: 47.728
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  5 in total

Review 1.  The role of miRNAs in cholangiocarcinoma.

Authors:  Jessica A Howell; Shahid A Khan
Journal:  Hepat Oncol       Date:  2016-03-29

2.  A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression.

Authors:  Heping Yang; Tony W H Li; Jian Peng; Xiaoli Tang; Kwang Suk Ko; Meng Xia; Maria-Angeles Aller
Journal:  Gastroenterology       Date:  2011-03-24       Impact factor: 22.682

Review 3.  Non-small-cell lung cancer harbouring mutations in the EGFR kinase domain.

Authors:  Rafael Rosell; Teresa Morán; Enric Carcereny; Vanessa Quiroga; Miguel Angel Molina; Carlota Costa; Susana Benlloch; Miquel Tarón
Journal:  Clin Transl Oncol       Date:  2010-02       Impact factor: 3.405

4.  Forced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of Apc(Min) mice.

Authors:  Yuji Takaoka; Yuko Shimizu; Hitoki Hasegawa; Yasuo Ouchi; Shanlou Qiao; Miki Nagahara; Masatoshi Ichihara; Jiing-Dwan Lee; Koichi Adachi; Michinari Hamaguchi; Takashi Iwamoto
Journal:  PLoS One       Date:  2012-08-02       Impact factor: 3.240

5.  Prognostic value of 12 m7G methylation-related miRNA markers and their correlation with immune infiltration in breast cancer.

Authors:  Wenchuan Zhang; Shuwan Zhang; Zhe Wang
Journal:  Front Oncol       Date:  2022-08-05       Impact factor: 5.738
  5 in total

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