Literature DB >> 19556168

Comparison of health care use and costs in newly diagnosed and established patients with fibromyalgia.

Leigh Ann White1, Rebecca L Robinson, Andrew P Yu, Anna Kaltenboeck, Seth Samuels, David Mallett, Howard G Birnbaum.   

Abstract

UNLABELLED: In 2004, the American Pain Society (APS) issued evidence-based fibromyalgia treatment recommendations. The objective of this claims database analysis is to describe prescription and medical use in patients with newly diagnosed and established fibromyalgia. Privately insured patients with 2+ myalgia/myositis claims (1999 to 2005) were categorized as newly diagnosed or established; this dichotomy involves comparisons between prediagnosis (S1) and postdiagnosis (S2) stages in the newly diagnosed and between newly diagnosed (S2) and established patients (S3). Use of APS guideline medications increased across stages: selective serotonin reuptake inhibitors (SSRIs) (S1, S2, S3: 20.6%, 22.9%, 25.3%), serotonin norepinephrine reuptake inhibitors (SNRIs) (4.5%, 6.4%, 8.9%), pregabalin/gabapentin (5.4%, 7.4%, 8.8%), benzodiazepines (19.0%, 21.1%, 24.2%), non-benzodiazepine sedatives (9.1%, 11.5%, 13.7%) (all P < .0001), and opioids (39.5%, 43.3%, 43.9%; S1 vs S2, P < .0001; S2 vs S3, P = .2835). Use of multiple therapeutic classes also increased across stages: 3+ classes (7.1%, 9.6%, 11.8%) (all P < .0001). Office visits to providers increased, on average, after diagnosis: primary care (70.9%, 78.3%, 76.3%; all P < .0001), chiropractors (28.8%, 51.1%, 53.3%; all P < .0001), rheumatologists (4.2%, 9.9%, 10.5%; S1 vs S2, P < .0001; S2 vs S3, P = .0595), mental health (6.4%, 7.3%, 8.3%; S1 vs S2, P < .0001, S2 vs S3, P = .0003). Average health care costs rose after diagnosis in the newly diagnosed group (S1: $6555 vs S2: $8654, P < .0001). PERSPECTIVE: This paper investigates prescription drug and medical care use with respect to stages of fibromyalgia diagnosis. Established fibromyalgia patients use more medical resources and have higher rates of concomitant medication use than newly diagnosed fibromyalgia patients. Findings can help educate providers regarding optimal drug treatment patterns in this population.

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Year:  2009        PMID: 19556168     DOI: 10.1016/j.jpain.2009.03.012

Source DB:  PubMed          Journal:  J Pain        ISSN: 1526-5900            Impact factor:   5.820


  7 in total

1.  Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.

Authors:  Seoyoung C Kim; Joan E Landon; Daniel H Solomon
Journal:  Arthritis Care Res (Hoboken)       Date:  2013-11       Impact factor: 4.794

Review 2.  Fibromyalgia: A Critical and Comprehensive Review.

Authors:  Andrea T Borchers; M Eric Gershwin
Journal:  Clin Rev Allergy Immunol       Date:  2015-10       Impact factor: 8.667

3.  Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.

Authors:  Seoyoung C Kim; Joan E Landon; Yvonne C Lee
Journal:  Arthritis Res Ther       Date:  2015-01-28       Impact factor: 5.156

4.  Evaluating increased resource use in fibromyalgia using electronic health records.

Authors:  Jay M Margolis; Elizabeth T Masters; Joseph C Cappelleri; David M Smith; Steven Faulkner
Journal:  Clinicoecon Outcomes Res       Date:  2016-11-16

5.  Fibromyalgia Outcomes Over Time: Results from a Prospective Observational Study in the United States.

Authors:  Caroline P Schaefer; Edgar H Adams; Margarita Udall; Elizabeth T Masters; Rachael M Mann; Shoshana R Daniel; Heather J McElroy; Joseph C Cappelleri; Andrew G Clair; Markay Hopps; Roland Staud; Philip Mease; Stuart L Silverman
Journal:  Open Rheumatol J       Date:  2016-11-30

6.  Applying standardized drug terminologies to observational healthcare databases: a case study on opioid exposure.

Authors:  Frank J Defalco; Patrick B Ryan; M Soledad Cepeda
Journal:  Health Serv Outcomes Res Methodol       Date:  2012-10-27

7.  Resource utilisation and direct costs in patients with recently diagnosed fibromyalgia who are offered one of three different interventions in a randomised pragmatic trial.

Authors:  Yvonne van Eijk-Hustings; Mariëlle Kroese; An Creemers; Robert Landewé; Annelies Boonen
Journal:  Clin Rheumatol       Date:  2015-09-26       Impact factor: 2.980

  7 in total

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