| Literature DB >> 19555053 |
Young Ku Kang1, Dae Young Kim.
Abstract
The catalytic enantioselective Mannich reaction promoted by chiral bifunctional organocatalysts is described. The treatment of beta-ketoesters with N-Boc-aldimines under mild reaction conditions afforded the corresponding beta-amino beta-ketoesters with excellent diastereoselectivities (up to 100:0 dr) and excellent enantioselectivities (up to 99% ee).Entities:
Mesh：
Substances：
Year: 2009 PMID： 19555053 DOI： 10.1021/jo900880t
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354