Literature DB >> 19554397

A false positive for metastatic lymph nodes in the axillary region of a breast cancer patient following mastectomy.

Nobuko Fujiuchi1, Toshiaki Saeki, Hideki Takeuchi, Hiroshi Sano, Takao Takahashi, Kazuo Matsuura, Takashi Shigekawa, Misono Misumi, Noriko Nakamiya, Katsuhiko Okubo, Akihiko Osaki, Takaki Sakurai, Hiroshi Matsuda.   

Abstract

Recent advanced imaging modalities such as positron emission tomography (PET) detect malignancies using 2-[18F]-fluoro-2-deoxy-D: -glucose (18-FDG) with high accuracy, and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false-positive metastatic lymph nodes that were diagnosed by PET/CT and ultrasonography in a 48-year-old breast cancer patient who had undergone mastectomy. The tumors, which were oval shaped and resembled lymph nodes, were detected by ultrasonography. PET/CT revealed high uptake of 18-FDG in the tumors. To investigate the proposed recurrence and to re-evaluate the biology of the recurrent tumors, a tumor was removed from the brachial plexus of the patient. Histological findings revealed it to be a schwannoma. All imaging modalities including PET/CT failed to distinguish benign tumors from metastatic lymph nodes in the brachial plexus. After resection of the schwannomas, the patient complained of a slight motor disorder of the second finger on the right hand. Hence, it is important to consider a false-positive case of lymph node metastasis in a breast cancer patient following mastectomy.

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Year:  2009        PMID: 19554397     DOI: 10.1007/s12282-009-0125-9

Source DB:  PubMed          Journal:  Breast Cancer        ISSN: 1340-6868            Impact factor:   4.239


  5 in total

1.  Brachial plexus tumor simulating an axillary metastasis from breast carcinoma.

Authors:  Anne Lynch; Gudrun Peters
Journal:  Radiol Case Rep       Date:  2015-12-07

2.  Axillary schwannoma mimicking lymph node metastasis-associated breast cancer: a case report.

Authors:  Hideki Kumagai; Kou Takehana; Yoshihiro Shioi; Chihiro Tono
Journal:  Surg Case Rep       Date:  2022-07-18

3.  False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report.

Authors:  Gamze Uğurluer; Mustafa Kibar; Sinan Yavuz; Akin Kuzucu; Meltem Serin
Journal:  Case Rep Med       Date:  2013-03-04

4.  Breast schwannoma in a patient with diffuse large B-cell lymphoma: a case report.

Authors:  Ayse Salihoglu; Sinem Nihal Esatoglu; Ahmet Emre Eskazan; Metin Halac; Seniz Ongoren Aydin
Journal:  J Med Case Rep       Date:  2012-12-17

5.  FDG-PET/CT of schwannomas arising in the brachial plexus mimicking lymph node metastasis: report of two cases.

Authors:  Takaaki Fujii; Reina Yajima; Hiroki Morita; Satoru Yamaguchi; Soichi Tsutsumi; Takayuki Asao; Hiroyuki Kuwano
Journal:  World J Surg Oncol       Date:  2014-10-12       Impact factor: 2.754

  5 in total

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