INTRODUCTION: We describe a case of genetically proven atypical teratoid/rhabdoid tumor (ATRT), showing ultrastructural evidence of ependymal differentiation. Such differentiation has not been reported so far in ATRT. CONCLUSION: This finding supports the concept that ATRTs as the majority of central nervous system embryonal tumors may derive from an immature and pluripotent neuroectodermal cell capable of differentiating along multiple lineages.
INTRODUCTION: We describe a case of genetically proven atypical teratoid/rhabdoid tumor (ATRT), showing ultrastructural evidence of ependymal differentiation. Such differentiation has not been reported so far in ATRT. CONCLUSION: This finding supports the concept that ATRTs as the majority of central nervous system embryonal tumors may derive from an immature and pluripotent neuroectodermal cell capable of differentiating along multiple lineages.
Authors: Geeta Chacko; Ari G Chacko; Christopher P Dunham; Alexander R Judkins; Jaclyn A Biegel; Arie Perry Journal: J Neurooncol Date: 2007-04-13 Impact factor: 4.130
Authors: Piergiorgio Modena; Elena Lualdi; Federica Facchinetti; Lisa Galli; Manuel R Teixeira; Silvana Pilotti; Gabriella Sozzi Journal: Cancer Res Date: 2005-05-15 Impact factor: 12.701
Authors: Roger J Packer; Jaclyn A Biegel; Susan Blaney; Jonathan Finlay; J Russell Geyer; Richard Heideman; Joanne Hilden; Anna J Janss; Larry Kun; Gilbert Vezina; Lucy B Rorke; Malcolm Smith Journal: J Pediatr Hematol Oncol Date: 2002 Jun-Jul Impact factor: 1.289