Literature DB >> 1955387

New antitumor substances, BE-12406A and BE-12406B, produced by a streptomycete. II. Structure determination.

S Nakajima1, K Kojiri, H Suda, M Okanishi.   

Abstract

The structure of BE-12406A and BE-12406B, which were isolated from the culture broth of a streptomycete as antitumor substances, were determined by means of spectral analyses and chemical studies. The structure of BE-12406A is 1-hydroxy-10-methoxy-8-methyl-12-alpha- L-rhamnopyranosyloxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one, and that of BE-12406B is 1,10-dihydroxy-8-methyl-12-alpha-L-rhamnopyranosyloxy-6H- benzo[d]naphtho[1,2-b]pyran-6-one.

Mesh：

Substances：

Year:  1991        PMID： 1955387     DOI： 10.7164/antibiotics.44.1061

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

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Authors:  Micah D Shepherd; Tao Liu; Carmen Méndez; Jose A Salas; Jürgen Rohr
Journal:  Appl Environ Microbiol       Date:  2010-11-12       Impact factor: 4.792

2.  Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate.

Authors:  Madan K Kharel; Hui Lian; Jürgen Rohr
Journal:  Org Biomol Chem       Date:  2011-01-24       Impact factor: 3.876

Review 3.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

4.  Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters.

Authors:  Madan K Kharel; S Eric Nybo; Micah D Shepherd; Jürgen Rohr
Journal:  Chembiochem       Date:  2010-03-01       Impact factor: 3.164

Review 5.  Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology.

Authors:  Madan K Kharel; Jürgen Rohr
Journal:  Curr Opin Chem Biol       Date:  2012-03-30       Impact factor: 8.822

6.  Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis.

Authors:  Pallab Pahari; Madan K Kharel; Micah D Shepherd; Steven G van Lanen; Jürgen Rohr
Journal:  Angew Chem Int Ed Engl       Date:  2011-12-23       Impact factor: 15.336

7.  Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion.

Authors:  Ming Ma; Mostafa E Rateb; Qihui Teng; Dong Yang; Jeffrey D Rudolf; Xiangcheng Zhu; Yong Huang; Li-Xing Zhao; Yi Jiang; Xiuling Li; Christoph Rader; Yanwen Duan; Ben Shen
Journal:  J Nat Prod       Date:  2015-09-03       Impact factor: 4.050

8.  Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity.

Authors:  Tao Liu; Madan K Kharel; Lili Zhu; Samuel A Bright; Cynthia Mattingly; Val R Adams; Jürgen Rohr
Journal:  Chembiochem       Date:  2009-01-26       Impact factor: 3.164

9.  Anti-cancer and antimicrobial potential of five soil Streptomycetes: a metabolomics-based study.

Authors:  Nada Osama; Walid Bakeer; Mai Raslan; Hanan A Soliman; Usama Ramadan Abdelmohsen; Mohamed Sebak
Journal:  R Soc Open Sci       Date:  2022-02-09       Impact factor: 2.963
  9 in total

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