OBJECTIVES: Infectious gastrointestinal disease (IGD) is a significant cause of morbidity in returned international travellers. This study aims to elucidate host and travel characteristics associated with IGD presentation, and describe the broad spectrum of aetiological pathogens responsible by geographic region of acquisition and reason for travel. METHODS: We analyzed demographic, clinical and microbiological data recorded for ill, returned international travellers presenting to GeoSentinel Surveillance Network sites globally during the period September 1996-December 2005. RESULTS: A total of 25,867 returned travellers were analyzed, of whom 7442 (29%) patients had a total of 8273 IGD diagnoses. Multivariate analysis demonstrated that IGD presentation was associated significantly with female sex (OR: 1.11; p=0.001); younger age group; attending a pre-travel medical appointment (OR: 1.28; p<0.0001); and travelling for the reason of tourism. Travelling for longer periods (>28 days) was associated with lower risk (OR: 0.93; p=0.04). Of the 2902 clinically significant pathogens isolated, 65% were parasitic, 31% bacterial and 3% viral. Presentation of IGD by specific pathogen varied markedly dependent on geographic region of recent travel, and reason for travel. CONCLUSIONS: Host characteristics, region of travel and category of traveller, significantly impact on the relative likelihood of presenting with a broad range of pathogen-specific IGD.
OBJECTIVES:Infectious gastrointestinal disease (IGD) is a significant cause of morbidity in returned international travellers. This study aims to elucidate host and travel characteristics associated with IGD presentation, and describe the broad spectrum of aetiological pathogens responsible by geographic region of acquisition and reason for travel. METHODS: We analyzed demographic, clinical and microbiological data recorded for ill, returned international travellers presenting to GeoSentinel Surveillance Network sites globally during the period September 1996-December 2005. RESULTS: A total of 25,867 returned travellers were analyzed, of whom 7442 (29%) patients had a total of 8273 IGD diagnoses. Multivariate analysis demonstrated that IGD presentation was associated significantly with female sex (OR: 1.11; p=0.001); younger age group; attending a pre-travel medical appointment (OR: 1.28; p<0.0001); and travelling for the reason of tourism. Travelling for longer periods (>28 days) was associated with lower risk (OR: 0.93; p=0.04). Of the 2902 clinically significant pathogens isolated, 65% were parasitic, 31% bacterial and 3% viral. Presentation of IGD by specific pathogen varied markedly dependent on geographic region of recent travel, and reason for travel. CONCLUSIONS: Host characteristics, region of travel and category of traveller, significantly impact on the relative likelihood of presenting with a broad range of pathogen-specific IGD.
Authors: Shanon M Smith; Lorena Montero; Maritza Paez; Estefania Ortega; Eric Hall; Kate Bohnert; Xavier Sanchez; Edison Puebla; Pablo Endara; William Cevallos; Gabriel Trueba; Karen Levy Journal: Trop Med Int Health Date: 2018-12-06 Impact factor: 2.622
Authors: Vanessa Field; Philippe Gautret; Patricia Schlagenhauf; Gerd-Dieter Burchard; Eric Caumes; Mogens Jensenius; Francesco Castelli; Effrossyni Gkrania-Klotsas; Leisa Weld; Rogelio Lopez-Velez; Peter de Vries; Frank von Sonnenburg; Louis Loutan; Philippe Parola Journal: BMC Infect Dis Date: 2010-11-17 Impact factor: 3.090
Authors: Philippe Gautret; Patricia Schlagenhauf; Jean Gaudart; Francesco Castelli; Philippe Brouqui; Frank von Sonnenburg; Louis Loutan; Philippe Parola Journal: Emerg Infect Dis Date: 2009-11 Impact factor: 6.883