Literature DB >> 19552735

Evaluation of endothelial function using finger plethysmography.

A K Faizi1, D W Kornmo, S Agewall.   

Abstract

BACKGROUND: The aims of this study were to establish the optimum duration of blood flow occlusion to obtain maximal response and to compare the response after lower-arm and upper-arm occlusion.
METHODS: Pulse wave amplitude was analysed using a novel finger plethysmograph (EndoPat; Itamar). For measuring reactive hyperaemic index (RHI) induced by forearm cuff occlusion, 30 healthy subjects were examined at different days in a random order of four cuff occlusion times (1.5, 3, 5 and 8 min). RHI induced by 5 min upper-arm cuff occlusion was also measured in 20 subjects.
RESULTS: Average RHI was lower with 1.5 and 3 min forearm occlusion compared with 8 min forearm occlusion (P = 0.002 and P = 0.024). There was no significant difference between values of 5 min and 8 min forearm occlusion and between 5 min forearm and 5 min upper-arm occlusion (P = 0.1). All subjects reported less discomfort after forearm occlusion compared with upper-arm occlusion.
CONCLUSION: Maximum response was reached after 5 min of blood flow occlusion and therefore this occlusion time is recommended. The response after forearm and upper-arm occlusion did not differ significantly. Forearm occlusion might be preferred as this caused less discomfort.

Entities:  

Mesh:

Year:  2009        PMID: 19552735     DOI: 10.1111/j.1475-097X.2009.00882.x

Source DB:  PubMed          Journal:  Clin Physiol Funct Imaging        ISSN: 1475-0961            Impact factor:   2.273


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