Literature DB >> 19551389

Defenestration in children younger than 6 years old: mortality predictors in severe head trauma.

Jose Roberto Tude Melo1, Federico Di Rocco, Laudenor Pereira Lemos-Júnior, Thomas Roujeau, Bertrand Thélot, Christian Sainte-Rose, Philippe Meyer, Michel Zerah.   

Abstract

PURPOSE: This study aims to describe the characteristics of severe head injuries in children less than 6 years old, victims of falls from windows, and identify the main predictive factors of mortality in this population. PATIENTS AND METHODS: A cross-sectional study was designed through data derived from medical records of less than 6-year-old children victims of falls from windows presenting with a severe head injury defined by an initial Glasgow coma scale (GCS) < or =8, hospitalized at a Pediatric Trauma center level III, between January 2000 and December 2005. Statistical analysis used univariate analysis and multiple logistic regressions.
RESULTS: We identified 58 severe head injuries in children victims of falls from windows. The mean age was 2.8 +/- 1.4 years, with a male prevalence (64%); 48% of patients had a GCS < or =5; 62.1% had a Pediatric Trauma Score (PTS) < or =3 at hospital admission. The mortality rate was 41% (24/58) and most of them (88%; 21/24) died within 48 h. An increased death rate was noted in children admitted with hypoxemia (p = 0.001), low systolic blood pressure (p = 0.002), hypothermia (p = 0.0001), GCS < or =5 (p = 10(-5)), PTS < or =3 (p = 0.008), hyperglycemia (p = 0.023), coagulation disorders (p = 0.02), and initial intracranial pressure > or =20 mmHg (p = 0.03). Initial hypothermia, hyperglycemia, and coagulation disorders were the only independent predictive factors of mortality.
CONCLUSION: Severe head injuries resulting from falls from windows carry a high risk of mortality in less than 6-year-old children. Hypothermia, hyperglycemia, and coagulation's disorders are independent predictive factors of mortality. Early deaths could be considered as direct consequences of uncontrollable brain lesions.

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Year:  2009        PMID: 19551389     DOI: 10.1007/s00381-009-0924-5

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  44 in total

1.  Hypothermia.

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2.  Persistent hyperglycemia is predictive of outcome in critically ill trauma patients.

Authors:  Grant V Bochicchio; Jin Sung; Manjari Joshi; Kelly Bochicchio; Steven B Johnson; Walter Meyer; Thomas M Scalea
Journal:  J Trauma       Date:  2005-05

3.  Falls from heights among children: a retrospective review.

Authors:  M Lallier; S Bouchard; D St-Vil; J Dupont; M Tucci
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4.  The impact of hyperglycemia on patients with severe brain injury.

Authors:  Elan Jeremitsky; Laurel A Omert; C Michael Dunham; Jack Wilberger; Aurelio Rodriguez
Journal:  J Trauma       Date:  2005-01

5.  [Epidemiology of accidental falls from heights among children, Paris Region, May to September 2005].

Authors:  B Thélot; A Rigou; C Bonaldi; C Ricard; P Meyer
Journal:  Sante Publique       Date:  2006-12       Impact factor: 0.203

6.  Prognostic implications of hyperglycaemia in paediatric head injury.

Authors:  A Chiaretti; R De Benedictis; A Langer; C Di Rocco; C Bizzarri; A Iannelli; G Polidori
Journal:  Childs Nerv Syst       Date:  1998-09       Impact factor: 1.475

Review 7.  [Chest trauma: spectrum of lesions].

Authors:  C Beigelman-Aubry; S Baleato; M Le Guen; A-L Brun; P Grenier
Journal:  J Radiol       Date:  2008-11

8.  The prognostic value of transcranial Doppler studies in children with moderate and severe head injury.

Authors:  Fabien Trabold; Philippe G Meyer; Stéphane Blanot; Pierre A Carli; Gilles A Orliaguet
Journal:  Intensive Care Med       Date:  2003-11-05       Impact factor: 17.440

9.  Potential for head injuries in infants from low-height falls.

Authors:  Brittany Coats; Susan S Margulies
Journal:  J Neurosurg Pediatr       Date:  2008-11       Impact factor: 2.375

10.  Cerebral energy metabolism during transient hyperglycemia in patients with severe brain trauma.

Authors:  Pedro Diaz-Parejo; Nils Ståhl; Wangbin Xu; Peter Reinstrup; Urban Ungerstedt; Carl-Henrik Nordström
Journal:  Intensive Care Med       Date:  2003-03-25       Impact factor: 17.440

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  4 in total

Review 1.  Coagulopathy after severe pediatric trauma.

Authors:  Sarah C Christiaans; Amy L Duhachek-Stapelman; Robert T Russell; Steven J Lisco; Jeffrey D Kerby; Jean-François Pittet
Journal:  Shock       Date:  2014-06       Impact factor: 3.454

2.  Is therapeutic hypothermia beneficial for pediatric patients with traumatic brain injury? A meta-analysis.

Authors:  Chenkai Ma; Xiaoguang He; Lin Wang; Baocheng Wang; Qifeng Li; Feng Jiang; Jie Ma
Journal:  Childs Nerv Syst       Date:  2013-03-16       Impact factor: 1.475

3.  Pediatric falls from windows and balconies: incidents and risk factors as reported by newspapers in the United Arab Emirates.

Authors:  Michal Grivna; Hanan M Al-Marzouqi; Maryam R Al-Ali; Nada N Al-Saadi; Fikri M Abu-Zidan
Journal:  World J Emerg Surg       Date:  2017-10-16       Impact factor: 5.469

4.  Sibling Death after Being Thrown from Window by Brother with Autism: Defenestration, an Emerging High-Risk Behavior.

Authors:  Osman Sabuncuoglu; Mustafa Yasin Irmak; Nagehan Ucok Demir; Duygu Murat; Can Tumba; Yuksel Yilmaz
Journal:  Case Rep Psychiatry       Date:  2015-08-03
  4 in total

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