Literature DB >> 19550425

Apoptosis and cancer: the genesis of a research field.

Thomas G Cotter1.   

Abstract

In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate balance can lead to the development of cancer. This Timeline article focuses on how the field of apoptosis biology has developed in the context of its contribution to our understanding of cell death, or lack of it, in the development of malignant disease. It traces the course of research from key discoveries in fundamental biology to potential therapeutic applications.

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Year:  2009        PMID： 19550425     DOI： 10.1038/nrc2663

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  105 in total

Review 1.  Transcriptional regulation by p53: one protein, many possibilities.

Authors:  O Laptenko; C Prives
Journal:  Cell Death Differ       Date:  2006-06       Impact factor: 15.828

2.  Fas ligand-induced apoptosis as a mechanism of immune privilege.

Authors:  T S Griffith; T Brunner; S M Fletcher; D R Green; T A Ferguson
Journal:  Science       Date:  1995-11-17       Impact factor: 47.728

3.  Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.

Authors:  X Liu; C N Kim; J Yang; R Jemmerson; X Wang
Journal:  Cell       Date:  1996-07-12       Impact factor: 41.582

4.  Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked.

Authors:  J Yang; X Liu; K Bhalla; C N Kim; A M Ibrado; J Cai; T I Peng; D P Jones; X Wang
Journal:  Science       Date:  1997-02-21       Impact factor: 47.728

5.  Predictive value of P53, BCL-2, and BAX in advanced head and neck carcinoma.

Authors:  Susana Casado; Jerónimo Forteza; Severina Dominguez; M Teresa Abad; Isabel Perez; Iratxe Intxaurbe; J M del Campo; Rafael Lopez
Journal:  Am J Clin Oncol       Date:  2002-12       Impact factor: 2.339

Review 6.  Prognostic significance of apoptosis regulators in breast cancer.

Authors:  S Krajewski; M Krajewska; B C Turner; C Pratt; B Howard; J M Zapata; V Frenkel; S Robertson; Y Ionov; H Yamamoto; M Perucho; S Takayama; J C Reed
Journal:  Endocr Relat Cancer       Date:  1999-03       Impact factor: 5.678

Review 7.  Cell death: the significance of apoptosis.

Authors:  A H Wyllie; J F Kerr; A R Currie
Journal:  Int Rev Cytol       Date:  1980

8.  Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins.

Authors:  A M Verhagen; P G Ekert; M Pakusch; J Silke; L M Connolly; G E Reid; R L Moritz; R J Simpson; D L Vaux
Journal:  Cell       Date:  2000-07-07       Impact factor: 41.582

9.  bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.

Authors:  L H Boise; M González-García; C E Postema; L Ding; T Lindsten; L A Turka; X Mao; G Nuñez; C B Thompson
Journal:  Cell       Date:  1993-08-27       Impact factor: 41.582

10.  Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.

Authors:  E Yang; J Zha; J Jockel; L H Boise; C B Thompson; S J Korsmeyer
Journal:  Cell       Date:  1995-01-27       Impact factor: 41.582
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  252 in total

1.  Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.

Authors:  Emmanuele Ambrosi; Stefano Capaldi; Michele Bovi; Gianmaria Saccomani; Massimiliano Perduca; Hugo L Monaco
Journal:  Biochem J       Date:  2011-09-01       Impact factor: 3.857

2.  Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8.

Authors:  Catherine L Watkins; Edward J Sayers; Chris Allender; David Barrow; Christopher Fegan; Paul Brennan; Arwyn T Jones
Journal:  Mol Ther       Date:  2011-09-20       Impact factor: 11.454

Review 3.  c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.

Authors:  Chenguang Wang; Yanhong Tai; Michael P Lisanti; D Joshua Liao
Journal:  Cancer Biol Ther       Date:  2011-04-01       Impact factor: 4.742

4.  Different effects of histone deacetylase inhibitors nicotinamide and trichostatin A (TSA) in C17.2 neural stem cells.

Authors:  Haifeng Wang; Hua Cheng; Kai Wang; Tieqiao Wen
Journal:  J Neural Transm (Vienna)       Date:  2012-03-13       Impact factor: 3.575

5.  Systematic evaluation of apoptotic pathway gene polymorphisms and lung cancer risk.

Authors:  Jie Lin; Charles Lu; David J Stewart; Jian Gu; Maosheng Huang; David W Chang; Scott M Lippman; Xifeng Wu
Journal:  Carcinogenesis       Date:  2012-06-04       Impact factor: 4.944

6.  Biophotonic probing of macromolecular transformations during apoptosis.

Authors:  Artem Pliss; Andrey N Kuzmin; Aliaksandr V Kachynski; Paras N Prasad
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-06       Impact factor: 11.205

7.  Selective induction of tumor cell apoptosis by a novel P450-mediated reactive oxygen species (ROS) inducer methyl 3-(4-nitrophenyl) propiolate.

Authors:  Xiaoxiao Sun; Midan Ai; Ying Wang; Shensi Shen; Yuan Gu; Yi Jin; Zuyu Zhou; Yaqiu Long; Qiang Yu
Journal:  J Biol Chem       Date:  2013-02-04       Impact factor: 5.157

8.  Lipid-conjugated Smac analogues.

Authors:  Ewa D Micewicz; Josephine A Ratikan; Alan J Waring; Julian P Whitelegge; William H McBride; Piotr Ruchala
Journal:  Bioorg Med Chem Lett       Date:  2015-09-08       Impact factor: 2.823

9.  Regulation of ferroptotic cancer cell death by GPX4.

Authors:  Wan Seok Yang; Rohitha SriRamaratnam; Matthew E Welsch; Kenichi Shimada; Rachid Skouta; Vasanthi S Viswanathan; Jaime H Cheah; Paul A Clemons; Alykhan F Shamji; Clary B Clish; Lewis M Brown; Albert W Girotti; Virginia W Cornish; Stuart L Schreiber; Brent R Stockwell
Journal:  Cell       Date:  2014-01-16       Impact factor: 41.582

10.  FOXL2 suppresses proliferation, invasion and promotes apoptosis of cervical cancer cells.

Authors:  Xing-Long Liu; Yu-Han Meng; Jian-Li Wang; Biao-Bing Yang; Fan Zhang; Sheng-Jian Tang
Journal:  Int J Clin Exp Pathol       Date:  2014-03-15
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