Literature DB >> 19550114

GCPReg package for registration of the segmentation gene expression data in Drosophila.

Konstantin N Kozlov1, Ekaterina Myasnikova, Anastasia A Samsonova, Svetlana Surkova, John Reinitz, Maria Samsonova.   

Abstract

In modern functional genomics registration techniques areused to construct reference gene expression patterns and createa spatiotemporal atlas of the expression of all the genes in anetwork. In this paper we present a software package calledGCPReg, which can be used to register the expression patterns ofsegmentation genes in the early Drosophila embryo. The key task,which this package performs, is the extraction of spatially localizedcharacteristic features of expression patterns. To facilitatethis task, we have developed an easy-to-use interactive graphicalinterface. We describe GCPReg usage and demonstrate how thispackage can be applied to register gene expression patterns inwild type and mutants. GCPReg has been designed to operate ona UNIX platform and is freely available via the Internet at http://urchin.spbcas.ru/downloads/GCPReg/GCPReg.htm.

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Year:  2009        PMID: 19550114      PMCID: PMC3171190          DOI: 10.4161/fly.8599

Source DB:  PubMed          Journal:  Fly (Austin)        ISSN: 1933-6934            Impact factor:   2.160


  20 in total

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