Literature DB >> 19549499

Antigenic variation: extending the reach of telomeric silencing.

David Horn1.   

Abstract

Immune evasion in the parasitic African trypanosome relies upon the silencing of variant surface glycoprotein genes that are found adjacent to telomeres. Work on the RAP1 telomere-binding protein now indicates that silencing spreads over a sufficient distance to repress these genes.

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Year:  2009        PMID： 19549499     DOI： 10.1016/j.cub.2009.04.049

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  5 in total

1.  Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution.

Authors:  Thomas Cavalier-Smith
Journal:  Biol Direct       Date:  2010-02-04       Impact factor: 4.540

2.  The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei.

Authors:  Viola Denninger; Alexander Fullbrook; Mohamed Bessat; Klaus Ersfeld; Gloria Rudenko
Journal:  Mol Microbiol       Date:  2010-09-02       Impact factor: 3.501

3.  NLP is a novel transcription regulator involved in VSG expression site control in Trypanosoma brucei.

Authors:  Mani Shankar Narayanan; Manish Kushwaha; Klaus Ersfeld; Alexander Fullbrook; Tara M Stanne; Gloria Rudenko
Journal:  Nucleic Acids Res       Date:  2010-11-13       Impact factor: 16.971

4.  Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes.

Authors:  Qiao-Ping Wang; Taemi Kawahara; David Horn
Journal:  Mol Microbiol       Date:  2010-09       Impact factor: 3.501

5.  Uncoupling transcription from covalent histone modification.

Authors:  Hesheng Zhang; Lu Gao; Jayamani Anandhakumar; David S Gross
Journal:  PLoS Genet       Date:  2014-04-10       Impact factor: 5.917
  5 in total

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