Literature DB >> 195473

Somatostatin-immunoreactive cells in medullary carcinoma of the thyroid.

F Sundler, J Alumets, R Håkanson, L Björklund, O Ljungberg.   

Abstract

Ten medullary carcinomas of the thyroid were examined by immunohistochemistry using antisera against calcitonin, somatostatin, and ACTH. In addition to calcitonin cells, eight of the tumors contained somatostatin-immunoreactive cells in varying numbers. No ACTH-immunoreactive cells were found. The results indicate that thyroid medullary carcinomas often are multihormonal, and that somatostatin is common in such tumors. In contrast to calcitonin cells, somatostatin cells are not found in normal human thyroid tissue.

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Year:  1977        PMID： 195473      PMCID： PMC2032172     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


  16 in total

1.  Immuno-fluorescent reactivity to anti-somatostatin in the gastro-intestinal mucosa of the dog.

Authors:  C Rufener; M P Dubois; F Malaisse Lagae; L Oric
Journal:  Diabetologia       Date:  1975-08       Impact factor: 10.122

2.  Letter: Immunohistochemical localization of somatostatin in the rat pancreas.

Authors:  G Pelletier; R Leclerc; A Arimura; A V Schally
Journal:  J Histochem Cytochem       Date:  1975-09       Impact factor: 2.479

3.  Evidence for the D-cell of the pancreas secreting somatostatin.

Authors:  L Orci; D Baetens; M P Dubois; C Rufener
Journal:  Horm Metab Res       Date:  1975-09       Impact factor: 2.936

4.  Some aspects of silver impregnation of the islets of Langerhans in the rat.

Authors:  C HELLERSTROEM; B HELLMAN
Journal:  Acta Endocrinol (Copenh)       Date:  1960-12

5.  Peptides with NH2-terminal tryptophan in adrenocorticotrophic hormone and melanocyte-stimulating hormone granules of adenohypophysis.

Authors:  R Håkanson; F Sundler; L I Larsson; R Ekman; N O Sjöberg
Journal:  J Histochem Cytochem       Date:  1975-01       Impact factor: 2.479

6.  Mixed endocrine pancreatic tumors producing several peptide hormones.

Authors:  L I Larsson; L Grimelius; R Håkanson; J F Rehfeld; F Stadil; J Holst; L Angervall; F Sundler
Journal:  Am J Pathol       Date:  1975-05       Impact factor: 4.307

7.  Immunohistochemical localization of somatostatin in endocrine cells of the rat stomach.

Authors:  R Leclerc; G Pelletier; R Puviani; A Arimura; A V Schally
Journal:  Mol Cell Endocrinol       Date:  1976-03       Impact factor: 4.102

8.  Calcitonin- and ACTH-producing cells in a case of medullary carcinoma of the thyroid. Immunofluorescence investigations.

Authors:  G Bussolati; S van Noorden; C Bordi
Journal:  Virchows Arch A Pathol Pathol Anat       Date:  1973-08-09

9.  Plasma-immunoreactive-calcitonin in patients with non-thyroid tumours.

Authors:  R C Coombes; C Hillyard; P B Greenberg; I MacIntyre
Journal:  Lancet       Date:  1974-06-01       Impact factor: 79.321

10.  A silver nitrate stain for alpha-2 cells in human pancreatic islets.

Authors:  L Grimelius
Journal:  Acta Soc Med Ups       Date:  1968
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  10 in total

1.  Immunohistochemical study of medullary thyroid carcinoma: relationship of clinical features to prognostic factors in 36 patients.

Authors:  H Takami; T Bessho; T Kameya; T Mimura; K Ito; O Abe; Y Hosoda; J Shikata
Journal:  World J Surg       Date:  1988-08       Impact factor: 3.352

2.  Ontogeny and ultrastructure of somatostatin and calcitonin cells in the thyroid gland of the rat.

Authors:  J Alumets; R Håkanson; G Lundqvist; F Sundler; J Thorell
Journal:  Cell Tissue Res       Date:  1980       Impact factor: 5.249

3.  Parafollicular cells of rabbit thryoid store both calcitonin and somatostatin and resemble gut D cells ultrastructurally.

Authors:  R Buffa; J A Chayvialle; P Fontana; L Usellini; C Capella; E Solcia
Journal:  Histochemistry       Date:  1979-08

4.  Production of gastrin releasing peptide by medullary carcinoma of the thyroid. An immunohistochemical study.

Authors:  T Kameya; T Bessho; M Tsumuraya; K Yamaguchi; K Abe; Y Shimosato; N Yanaihara
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1983

5.  Medullary thyroid carcinoma in female BALB/c mice. A report of 3 cases with ultrastructural, immunohistochemical, and transplantation data.

Authors:  M J Van Zwieten; C H Frith; A L Nooteboom; H J Wolfe; R A Delellis
Journal:  Am J Pathol       Date:  1983-02       Impact factor: 4.307

6.  Jejunal endocrine tumor composed of somatostatin and gastrin cells and associated with duodenal ulcer disease.

Authors:  J Alumets; G Ekelund; R Håkanson; O Ljungberg; U Ljungqvist; F Sundler; S Tibblin
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1978-05-05

7.  Somatostatin-like immunoreactivity in rat thyroid. Age-associated S-cell hyperplasia.

Authors:  K Kakudo; K Uematsu; K Sakurai; M Suehiro; M Fukuchi
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

8.  Ultrastructural and electron immunohistochemical features of medullary thyroid carcinoma.

Authors:  R Holm; G W Farrants; J M Nesland; M Sobrinho-Simões; O G Jørgensen; J V Johannessen
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

9.  Comparative distribution of somatostatin and somatostatin receptors in PTU-induced hypothyroidism.

Authors:  Sneha Singh; Rishi K Somvanshi; Vandana Panda; Ujendra Kumar
Journal:  Endocrine       Date:  2020-04-25       Impact factor: 3.633

10.  Immunoreactive somatostatin in Warthin's tumor.

Authors:  Y Hayashi; H Saito; S Saito; T Yanagawa; H Yoshida; Y Yura; M Sato
Journal:  Am J Pathol       Date:  1986-05       Impact factor: 4.307
  10 in total

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