| Literature DB >> 19545615 |
Mi Zhang1, Man Chen, Han-Qing Zhang, Shi Sun, Bing Xia, Fei-Hua Wu.
Abstract
Moracin M (1), Steppogenin-4'-O-beta-D-glucosiade (2), Mullberroside A (3) were isolated from the root bark of Morus alba L. and identified by spectral evidence. Compounds 1, 2 and 3 were studied in hypoglycemic effects on alloxan-diabetic mice. The results showed that compounds 1, 2 and 3 all produced hypoglycemic effects. The compound 2 in a dose of 50 mg/kg exerted significant effect (p<0.05), 2 and 3 in a dose of 100 mg/kg exerted obviously effect (p<0.01). Meantime, the compound 1 in a dose of 100 mg/kg can make the fasting blood glucose level have decreasing tendency.Entities:
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Year: 2009 PMID： 19545615 DOI： 10.1016/j.fitote.2009.06.009
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882