Cynthia J Mears1, Elisa N Lawler, Lee D Sanders, Ben Z Katz. 1. Children's Memorial Hospital, Northwestern University, Feinberg School of Medicine, General Academic Pediatrics, 2300 Children's Plaza, Box 16, Chicago, IL 60614-3363, USA. c-mears@northwestern.edu
Abstract
PURPOSE: To determine the effectiveness of the intranasal LAIV-T in decreasing school absenteeism in a school-based vaccination initiative and to compare the acceptability of LAIV-T versus TIV among adolescents. METHODS: This study was conducted within a single, urban community high school in the Fall of 2006. Participation was offered to all students in grades 6 to 10, aged 11 to 17 years. In December, school health center staff administered influenza vaccines to the students whose parents had returned written consent. Students received LAIV-T (n = 86), unless they were medically ineligible or objected; in those cases the injectable inactivated trivalent influenza vaccine (TIV) (n = 41) was offered. Students that did not receive either vaccination served as a control group (n = 234). Nonsuspension absences between January and June of 2007 were tracked for all three groups. RESULTS: Students who received the LAIV-T had significantly less nonsuspension absences (mean absences = 5.53, SD = 5.00) compared to both the TIV (mean absences = 9.45, SD = 9.07) and control groups (mean absences = 7.97, SD =7.59). CONCLUSIONS: LAIV-T was associated with a reduction in nonsuspension absences and was well accepted by students. Administration of LAIV-T may be a convenient and effective method to mass-immunize students in a school setting and help establish herd immunity within the community.
PURPOSE: To determine the effectiveness of the intranasal LAIV-T in decreasing school absenteeism in a school-based vaccination initiative and to compare the acceptability of LAIV-T versus TIV among adolescents. METHODS: This study was conducted within a single, urban community high school in the Fall of 2006. Participation was offered to all students in grades 6 to 10, aged 11 to 17 years. In December, school health center staff administered influenza vaccines to the students whose parents had returned written consent. Students received LAIV-T (n = 86), unless they were medically ineligible or objected; in those cases the injectable inactivated trivalent influenza vaccine (TIV) (n = 41) was offered. Students that did not receive either vaccination served as a control group (n = 234). Nonsuspension absences between January and June of 2007 were tracked for all three groups. RESULTS: Students who received the LAIV-T had significantly less nonsuspension absences (mean absences = 5.53, SD = 5.00) compared to both the TIV (mean absences = 9.45, SD = 9.07) and control groups (mean absences = 7.97, SD =7.59). CONCLUSIONS:LAIV-T was associated with a reduction in nonsuspension absences and was well accepted by students. Administration of LAIV-T may be a convenient and effective method to mass-immunize students in a school setting and help establish herd immunity within the community.
Authors: Sara Boccalini; Elena Pariani; Giovanna Elisa Calabrò; Chiara DE Waure; Donatella Panatto; Daniela Amicizia; Piero Luigi Lai; Caterina Rizzo; Emanuele Amodio; Francesco Vitale; Alessandra Casuccio; Maria Luisa DI Pietro; Cristina Galli; Laura Bubba; Laura Pellegrinelli; Leonardo Villani; Floriana D'Ambrosio; Marta Caminiti; Elisa Lorenzini; Paola Fioretti; Rosanna Tindara Micale; Davide Frumento; Elisa Cantova; Flavio Parente; Giacomo Trento; Sara Sottile; Andrea Pugliese; Massimiliano Alberto Biamonte; Duccio Giorgetti; Marco Menicacci; Antonio D'Anna; Claudia Ammoscato; Emanuele LA Gatta; Angela Bechini; Paolo Bonanni Journal: J Prev Med Hyg Date: 2021-09-10
Authors: Frank Andersohn; Reinhard Bornemann; Oliver Damm; Martin Frank; Thomas Mittendorf; Ulrike Theidel Journal: GMS Health Technol Assess Date: 2014-10-30