Literature DB >> 19541000

A facile three-component solid phase synthesis of steroidal A-ring fused pyrimidines under microwave irradiation.

Madan G Barthakur1, Shyamalee Gogoi, Mandakini Dutta, Romesh C Boruah.   

Abstract

The preparation of ring-A fused pyrimidines at the steroidal 2,3-position is herein described. The novel steroidal pyrimidines were prepared from the solid phase three-component reaction of 2-hydroxymethylene-3-keto steroids, arylaldehydes and ammonium acetate under microwave irradiation.

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Year:  2009        PMID: 19541000     DOI: 10.1016/j.steroids.2009.03.006

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  3 in total

1.  Evaluation of Neurotropic Activity and Molecular Docking Study of New Derivatives of pyrano[4″,3″:4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidines on the Basis of pyrano[3,4-c]pyridines.

Authors:  Shushanik Sh Dashyan; Eugene V Babaev; Ervand G Paronikyan; Armen G Ayvazyan; Ruzanna G Paronikyan; Lernik S Hunanyan
Journal:  Molecules       Date:  2022-05-24       Impact factor: 4.927

2.  7-Aza-des-A-steroids with Antimicrobial and Cytotoxic Activity.

Authors:  Melanie Krojer; Marco Keller; Franz Bracher
Journal:  Sci Pharm       Date:  2013-04-14

3.  Steroidal Pyrimidines and Dihydrotriazines as Novel Classes of Anticancer Agents against Hormone-Dependent Breast Cancer Cells.

Authors:  Alexander M Scherbakov; Alexander V Komkov; Anna S Komendantova; Margarita A Yastrebova; Olga E Andreeva; Valerii Z Shirinian; Alakananda Hajra; Igor V Zavarzin; Yulia A Volkova
Journal:  Front Pharmacol       Date:  2018-01-10       Impact factor: 5.810

  3 in total

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