BACKGROUND: Marked changes in the prevalence of noncommunicable diseases such as obesity, diabetes, and cardiovascular disease have occurred in developed and developing countries in recent decades. The overarching aim of the study is to examine the relationship of societal influences on human lifestyle behaviors, cardiovascular risk factors, and incidence of chronic noncommunicable diseases. METHODS: The Prospective Urban Rural Epidemiology (PURE) study is a large-scale epidemiological study that plans to recruit approximately 140,000 individuals residing in >600 communities in 17 low-, middle-, and high-income countries around the world. Individual data collection includes medical history, lifestyle behaviors (physical activity and dietary profile), blood collection and storage for biochemistry and future genetic analysis, electrocardiogram, and anthropometric measures. In addition, detailed information is being collected with respect to 4 environmental domains of interest-the built environment, nutrition and associated food policy, psychosocial/socioeconomic factors, and tobacco environment. A minimum follow-up of 10 years is currently planned. RESULTS: This report describes the design, justification, and methodology of the PURE study. The PURE study has been recruiting since 2002 and has enrolled 139,506 individuals by March 31, 2009. CONCLUSIONS: The PURE study builds on the work and experience gained through conduct of the INTERHEART study. Its design and extensive data collection are geared toward addressing major questions on causation and development of the underlying determinants of cardiovascular disease in populations at varying stages of epidemiologic transition.
BACKGROUND: Marked changes in the prevalence of noncommunicable diseases such as obesity, diabetes, and cardiovascular disease have occurred in developed and developing countries in recent decades. The overarching aim of the study is to examine the relationship of societal influences on human lifestyle behaviors, cardiovascular risk factors, and incidence of chronic noncommunicable diseases. METHODS: The Prospective Urban Rural Epidemiology (PURE) study is a large-scale epidemiological study that plans to recruit approximately 140,000 individuals residing in >600 communities in 17 low-, middle-, and high-income countries around the world. Individual data collection includes medical history, lifestyle behaviors (physical activity and dietary profile), blood collection and storage for biochemistry and future genetic analysis, electrocardiogram, and anthropometric measures. In addition, detailed information is being collected with respect to 4 environmental domains of interest-the built environment, nutrition and associated food policy, psychosocial/socioeconomic factors, and tobacco environment. A minimum follow-up of 10 years is currently planned. RESULTS: This report describes the design, justification, and methodology of the PURE study. The PURE study has been recruiting since 2002 and has enrolled 139,506 individuals by March 31, 2009. CONCLUSIONS: The PURE study builds on the work and experience gained through conduct of the INTERHEART study. Its design and extensive data collection are geared toward addressing major questions on causation and development of the underlying determinants of cardiovascular disease in populations at varying stages of epidemiologic transition.
Authors: Sasiragha P Reddy; Ken Resnicow; Shamagonam James; Itumeleng N Funani; Nilen S Kambaran; Riyadh G Omardien; Pardon Masuka; Ronel Sewpaul; Roger D Vaughan; Anthony Mbewu Journal: Am J Public Health Date: 2011-11-28 Impact factor: 9.308
Authors: Perry Hystad; Andrew Larkin; Sumathy Rangarajan; Khalid F AlHabib; Álvaro Avezum; Kevser Burcu Tumerdem Calik; Jephat Chifamba; Antonio Dans; Rafael Diaz; Johan L du Plessis; Rajeev Gupta; Romaina Iqbal; Rasha Khatib; Roya Kelishadi; Fernando Lanas; Zhiguang Liu; Patricio Lopez-Jaramillo; Sanjeev Nair; Paul Poirier; Omar Rahman; Annika Rosengren; Hany Swidan; Lap Ah Tse; Li Wei; Andreas Wielgosz; Karen Yeates; Khalid Yusoff; Tomasz Zatoński; Rick Burnett; Salim Yusuf; Michael Brauer Journal: Lancet Planet Health Date: 2020-06
Authors: Pablo M Lamelas; Andrew Mente; Rafael Diaz; Andres Orlandini; Alvaro Avezum; Gustavo Oliveira; Fernando Lanas; Pamela Seron; Patricio Lopez-Jaramillo; Paul Camacho-Lopez; Martin J O Donnell; Sumathy Rangarajan; Koon Teo; Salim Yusuf Journal: Am J Hypertens Date: 2015-12-18 Impact factor: 2.689