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Literature DB >> 19540203

Role of specific microRNAs for endothelial function and angiogenesis.

Abstract

Accumulating evidence indicates that various aspects of angiogenesis, such as proliferation, migration, and morphogenesis of endothelial cells, can be regulated by specific miRNAs in an endothelial-specific manner. As novel molecular targets, miRNAs have a potential value for treatment of angiogenesis-associated diseases such as cancers, inflammation, and vascular diseases. In this article, we review the latest advances in the identification and validation of angiogenesis-regulatory miRNAs and their targets, and discuss their roles and mechanisms in regulating endothelial cell function and angiogenesis.

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Year: 2009 PMID： 19540203 PMCID： PMC2821898 DOI： 10.1016/j.bbrc.2009.06.075

Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575

51 in total

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Authors: Angelika Kuehbacher; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
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3. Intronic microRNA precursors that bypass Drosha processing.

Authors: J Graham Ruby; Calvin H Jan; David P Bartel
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5. Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92.

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Journal: Oncogene Date: 2007-03-26 Impact factor: 9.867

6. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells.

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7. The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences.

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8. Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy.

Authors: Mariko Tatsuguchi; Hee Young Seok; Thomas E Callis; J Michael Thomson; Jian-Fu Chen; Martin Newman; Mauricio Rojas; Scott M Hammond; Da-Zhi Wang
Journal: J Mol Cell Cardiol Date: 2007-04-14 Impact factor: 5.000

9. MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression.

Authors: Daniel Y Lee; Zhaoqun Deng; Chia-Hui Wang; Burton B Yang
Journal: Proc Natl Acad Sci U S A Date: 2007-12-11 Impact factor: 11.205

10. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia.

Authors: Zhong Hua; Qing Lv; Wenbin Ye; Chung-Kwun Amy Wong; Guoping Cai; Dayong Gu; Yanhong Ji; Chen Zhao; Jifeng Wang; Burton B Yang; Yaou Zhang
Journal: PLoS One Date: 2006-12-27 Impact factor: 3.240

53 in total

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Review 3. Tracking miRNAs' footprints in tumor-microenvironment interactions: Insights and implications for targeted cancer therapy.

Authors: Nazila Nouraee; Seyed Javad Mowla; George A Calin
Journal: Genes Chromosomes Cancer Date: 2015-03-31 Impact factor: 5.006

4. Interactome of miRNAs and transcriptome of human umbilical cord endothelial cells exposed to short-term simulated microgravity.

Authors: Dharanibalan Kasiviswanathan; Rajadurai Chinnasamy Perumal; Srinivasan Bhuvaneswari; Pavitra Kumar; Lakshmikirupa Sundaresan; Manuel Philip; Sajesh Puthenpurackal Krishnankutty; Suvro Chatterjee
Journal: NPJ Microgravity Date: 2020-07-30 Impact factor: 4.415