OBJECTIVE: Periodic leg movements during sleep (PLMS) have been shown to be associated with changes in autonomic and hemispheric activities. Near infrared spectroscopy (NIRS) assesses hemodynamic changes linked to hemispheric/cortical activity. We applied NIRS to test whether cerebral hemodynamic alterations accompany PLMS. METHODS: Three PLMS patients underwent nocturnal polysomnography coupled with cerebral NIRS. EEG correlates of PLMS were scored and NIRS data were analysed for the identification of correspondent hemodynamic changes. RESULTS: PLMS were constantly associated with cerebral hemodynamic fluctuations that showed greater amplitude when associated to changes in EEG and were present also in absence of any visually detectable arousal or A phase in the EEG. CONCLUSION: This is the first study documenting cerebral hemodynamic changes linked to PLMS. SIGNIFICANCE: The clinical relevance of these observations remains to be determined.
OBJECTIVE: Periodic leg movements during sleep (PLMS) have been shown to be associated with changes in autonomic and hemispheric activities. Near infrared spectroscopy (NIRS) assesses hemodynamic changes linked to hemispheric/cortical activity. We applied NIRS to test whether cerebral hemodynamic alterations accompany PLMS. METHODS: Three PLMS patients underwent nocturnal polysomnography coupled with cerebral NIRS. EEG correlates of PLMS were scored and NIRS data were analysed for the identification of correspondent hemodynamic changes. RESULTS: PLMS were constantly associated with cerebral hemodynamic fluctuations that showed greater amplitude when associated to changes in EEG and were present also in absence of any visually detectable arousal or A phase in the EEG. CONCLUSION: This is the first study documenting cerebral hemodynamic changes linked to PLMS. SIGNIFICANCE: The clinical relevance of these observations remains to be determined.
Authors: Valerie E Rogers; Carole L Marcus; Abbas F Jawad; Kim Smith-Whitley; Kwaku Ohene-Frempong; Cheryl Bowdre; Julian Allen; Raanan Arens; Thornton B A Mason Journal: Sleep Date: 2011-07-01 Impact factor: 5.849
Authors: Mark I Boulos; Brian J Murray; Ryan T Muir; Fuqiang Gao; Gregory M Szilagyi; Menal Huroy; Alexander Kiss; Arthur S Walters; Sandra E Black; Andrew S Lim; Richard H Swartz Journal: Sleep Date: 2017-03-01 Impact factor: 5.849